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Codagenix Inks Exclusive License Agreement
November 30, 2016
Codagenix, Inc. has entered into an exclusive licensing agreement with Stony Brook University, through the Research Foundation for the State of New York, to commercialize a platform technology to develop a pipeline of live attenuated vaccines against viral infections in people and animals. The technology relies on software to re-design the genomes of potentially harmful viruses to make them safe and effective vaccines. The technology stems from research in the laboratory of Eckard Wimmer, PhD, Distinguished Professor in the Department of Molecular Genetics & Microbiology. The lead indication for vaccine development generated is a vaccine against Seasonal Influenza slated for Phase I human clinical trials in 2017.
Dr. Wimmer, along with Steffen Mueller, PhD, Codagenix President and Chief Science Officer, and J. Robert Coleman, PhD, Codagenix Chief Operating officer, worked as colleagues for years in Dr. Wimmer’s laboratory examining and experimenting with the genes of viruses. By collaborating with Stony Brook scientists Bruce Futcher, PhD, in the Department of Molecular Genetics & Microbiology, and Steven Skienna, PhD, in the Department of Computer Science, they discovered a way using gene manipulation and computer algorithms to “re-code” the genes of viruses. This re-coding process makes viruses extremely weak and thus ideal candidates as ultra-low dose attenuated vaccines.
The licensing agreement enables Codgenix to develop and potentially market next generation vaccines using software-based gene design and whole viral synthesis to create low-dose, attenuated virus vaccines. The company expects to use this design to first test its vaccine against influenza; however, there are plans for human testing of their Zika and other vaccine candidates. Codagenix is also in partnership with a large agricultural company to make vaccines using the technology for companion and agricultural animals.
The technology has been shown to be effective against numerous viruses including ZIka, Dengue, and RSV all of which are in preclinical testing. The development of this pipeline of vaccines can be seen in numerous scientific papers since 2008, including a paper in Science, PNAS, National Biotechnology and most recently in 2015 in MBIo.
Read Stony Brook University’s full press release here.
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Wednesday, May 26, 2021 | 2:00 PM-4:00 PM
BARDA DRIVe has launched a Mask Innovation Challenge to support the development of innovative solutions that can protect Americans from respiratory pathogens such as SARS-CoV-2.
The Center for Biotechnology, a BARDA DRIVe Accelerator Network site, is hosting this Mask Challenge event in partnership with the The Science Center, during which applicants who have made it past the first round will be pitching their mask design and plan for commercialization.
Register Here: https://venturecafeglobal-org.zoom.us/meeting/register/tJIvcOCvrzMiEtPblEbmB3cwezwMIleFe3xr
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The Center for Biotechnology has announced a Call for Proposals for our 2024 Applied Research and Development (ARAD) Program. The ARAD program provides matching funds on a competitive basis to support collaborations between Stony Brook University faculty and NY State corporate partners in all areas of medical biotechnology.
These areas include research technologies, diagnostics, therapeutics and medical devices. The primary interest is in supporting development of technologies that will help companies hit commercially relevant milestones, and that have the potential to positively impact the New York State economy.
2024 Proposal Submission:
The deadline for receipt of applications is May 15, 2024, 5pm. No exceptions will be made. Applications are accepted and considered on a competitive basis and are subject to the availability of funds. Approval from the Research Foundation Sponsored Programs is not required prior to submission, but will be required if the project is selected for funding. All applications require a letter-of-support from a senior executive of the company confirming their corporate residency in New York State and financial commitment to match-fund the project. Further details are found within the forms pages. A single PDF version of the proposal and letter of support should be submitted to the Center for Biotechnology at center_for_biotechnology@stonybrook.edu.
ARAD Program Forms:
Call for Applications & Guidelines
Application Form
Budget Forms
[post_title] => Call for Proposals: Applied Research and Development Program 2024
[post_excerpt] => 2024 Applied Research and Development (ARAD) Program RFP Released! The ARAD program provides matching funds on a support collaborations between Stony Brook University faculty and NY State corporate partners.
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[post_content] => Thinking of starting a life science company? The Center for Biotechnology can provide access to a compelling, pre-screened pipeline of academic technologies, milestone based incentives, access to early-stage funding opportunities, and staff support to serve as your virtual start-up team.
The Long Island, NY region has a well demonstrated capacity for innovation, serving as home to Cold Spring Harbor Laboratory, Stony Brook University, the Feinstein Institute at Northwell Health, and Brookhaven National Laboratory, among others. Sample technologies that have emerged from the region include Magnetic Resonance Imaging (MRI), ReoPro®; Xiaflex®; Cavistat®; Oracea®, and 3D Virtual Colonoscopy.
More details on the BioEntrepreneur-in-Residence initiative can be found here. Women and underrepresented minorities are encouraged to inquire. If you are interested in the initiative or would like to discuss further, please contact Diane Fabel at diane.fabel@stonybrook.edu or call 631.632.1582.
[post_title] => Call for Entrepreneurs!
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