Whether your personal interests are in supporting innovation, bringing lifesaving biomedical products to patients, training the next generation of biomedical leaders or fueling our economy, the Center for Biotechnology provides a vehicle to accomplish great things. Things that matter. Things that change, and save, lives.
Your involvement is an essential part of our future. Please consider a gift to the Center for Biotechnology which will help fuel innovation by ensuring that lifesaving technologies make it out of research labs and into the hands of patients.
Give to the Center for Biotechnology online through the Stony Brook Foundation. Contributions can be made to our Fund for Excellence. More information about donating through the Stony Brook Foundation can be found here.
Client News: First In-Human Clinical Trial Targeting CD4 Protein for Aggressive T-cell Leukemia and Lymphoma to be Launched
August 13, 2018
Stony Brook University, iCell Gene Therapeutics and University of Louisville collaborate to offer a new CAR T immunotherapy to treat patients.
Stony Brook University, iCell Gene Therapeutics, and the University of Louisville, have received Food and Drug Administration (FDA) clearance for an Investigational New Drug (IND) for the treatment of relapsed and refractory T-cell leukemia and lymphoma. The approach is the first to use chimeric antigen receptor engineered T-cells directed against the target protein CD4 (CD4CAR). Together, Stony Brook University, the University of Louisville, and iCell Gene Therapeutics expect the first in-human Phase I clinical trial to begin accruing patients before the end of 2018.
“We are excited to partner with the University of Louisville and iCell Gene Therapeutics to offer this innovative first-in-human CAR T cell immunotherapy clinical trial for patients who are suffering from these extremely difficult to treat T cell lymphomas and leukemias,” said Huda Salman, MD, Principal Investigator for the IND and an oncologist at Stony Brook University Cancer Center. “CD4CAR T cells may prove to be a promising and novel therapy in this setting.”
“The development of this trial using CD4 as a target is the first of what we expect to be many CAR T-based clinical trials available to our patients over time,” said Yusuf Hannun, MD, Director of the Stony Brook University Cancer Center. “The pending trial is an example of the type of bench-to-bedside research that is building up at Stony Brook due to the growing expertise and collaborative research environment we are creating and new opportunities that will emerge upon the opening of our Medical and Research Translation (MART) Building.”
William Tse, MD, FACP, Chief of the Blood and Marrow Transplantation at the University of Louisville School of Medicine, is the Co-PI of the CD4CAR clinical trial at University of Louisville site.
Join Stony Brook University’s Intellectual Property Partners on Thursday, October 12, from 4:30 pm to 6 pm at the Charles B. Wang Center at Stony Brook University for the panel discussion titled “Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing.”
The event will be hosted by Intellectual Property Partners (IPP), the SBU Chapter of the National Academy of Inventors (NAI), and the Manufacturing and Technology Resource Consortium (MTRC) and will be followed by a networking cocktail reception from 6 pm to 7 pm.
Moderated by Dr. James Hayward, President, CEO and Chairman of Applied DNA Sciences, panelists include: – Adrian Howansky, PhD, Clinical Medical Physicist, Department of Radiology, Stony Brook University Hospital – Doreen Swift, Senior Director, Embedded Software Engineering, IPS – Michael R. Bielski, President, DevTech Partners – Nariman Boyle, MD, Director, Ophthalmic Plastic Orbit and Reconstructive Surgery, Department of Ophthalmology, Renaissance School of Medicine, Stony Brook University – Paul Schwartz, Director, Advanced Propulsion Technologies
This event is free and open to Stony Brook University attendees. Space is limited and registration is required. Register here to secure your spot.
[post_title] => "Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing" 10/12/23
[post_excerpt] => Join Stony Brook University’s Intellectual Property Partners on October 12th for the panel discussion titled “Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing.”
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[post_content] => Accelerating the development of biomedical technologies
The Center for Biotechnology at Stony Brook University, on behalf of the Long Island Bioscience Hub (LIBH), has announced the recipients of the second round of funded projects under the Hub’s technology development and commercialization initiative. Funding for ten projects totaling $600,000 was awarded to applicants from the Hub’s partner institutions. Partner institutions include Stony Brook University, Cold Spring Harbor Laboratory, Brookhaven National Laboratory, and the Feinstein Institute at Northwell Health Systems.
The technology development awards made available by the LIBH are specifically aimed at growing a pipeline of commercially promising biomedical technologies that can be out-licensed for further development or serve as the foundation for new company formations in the region. There are two tiers of funding, each with the goal of accelerating technology development to reach a critical development inflection point. Feasibility awards ($50,000) are designed to rapidly test the feasibility of new ideas in a “fail-fast-or-proceed” format, or to add value to existing intellectual property leading to new market applications. Proof-of-Concept Awards ($100,000) provide targeted, milestone driven support for further development, testing, and analysis of existing intellectual property.
A wide range of disciplines are represented in the project awards this cycle including biomedical engineering, chemistry, biochemistry, psychiatry, molecular genetics and microbiology, and pathology and dermatology. Eight Feasibility awards and two Proof of Concepts awards have been funded this cycle. The recipients of this round of awards are:
Feasibility Awards
Therapeutic for Clostridium difficile antibiotic-associated diarrheal disease – Dr. James Bliska
Device for rapid, simple and highly parallel single-cell processing – Dr. Eric Brouzes
Developing a small molecule drug to treat systemic C. albicans infections – Dr. Nick Carpino
Next generation hedgehog inhibitor for invasive basal cell carcinoma – Dr. Jiang Chen
A Novel Strategy for Recombinant AAV Vector Production for Gene Therapy – Dr. Patrick Hearing
A tandem-integration-based multi-barcode method for high-throughput combinatorial screening – Dr. Sasha Levy
Novel CAIX Targeted Combination Inhibitor/PET tracer to treat patients with solid tumors – Dr. Peter Smith-Jones
Substrate-Assisted Tethered Inhibitors of LigA to Treat MDR Gonorrhea – Dr. Peter Tonge
Proof of Concept Awards
fMRI Dynamic Phantom for Improved Detection of Resting-State Brain Networks - Dr. Lilianne Mujica-Parodi
Development of SMASH technology as a next-gen sequencing diagnostic for congenital heart disease - Dr. Michael Ronemus
“The announcement of this second cycle of awards from the Long Island Bioscience Hub under the NIH-REACH program is exemplary of the increasing commercially relevant research taking place in the region” said Clinton T. Rubin, Ph.D., Distinguished Professor, Chair, Department of Biomedical Engineering, and Director, Center for Biotechnology. “Coupled with the recent expansion of the Hub to include the Feinstein Institute and the announcement of our third “request for proposals,” the LIBH is steadily working toward its goal of accelerating the translation of these technologies from the bench to the bed side.”
The main goal of the LIBH is to foster the development of therapeutics, preventatives, diagnostics, devices and research tools emerging from LIBH partner institutions that address diseases within the NIH’s mission.
Download a PDF of the press release here.
[post_title] => Long Island Bioscience Hub Announces Next Funded Projects
[post_excerpt] => The Center for Biotechnology, on Behalf of the Long Island Bioscience Hub (LIBH), has announced the recipients of the second round of funded projects under the Hub’s technology development and commercialization initiative. Funding for ten projects totaling $600,000 was awarded to applicants from the Hub’s partner institutions.
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The Center for Biotechnology on behalf of the Long Island Bioscience Hub is pleased to announce a request for proposals for our two-tiered technology development & commercialization program. Awards will be in two categories: Feasibility ($50k/12mo) and Proof of Concept ($100K/12 mo.) Details on the full funding program overview and proposal guidelines can be found here.
Faculty and postdoctoral associates, alone or in partnership with companies or CFB-appointed BioEntrepreneurs-in-Residence (BEIRs), are eligible to apply. In all instances, the faculty member or post-doctoral associate must serve as the principal investigator, and the project must be executed on the academic campus at Stony Brook University.
Application Deadline: Monday, July 18, 2022, 5pm ET
Interested applicants are strongly recommended to connect with the Center for Biotechnology team before writing a full proposal and submission. Please contact William Hanes, JD, PhD, at the Center for Biotechnology: William Hanes, JD, PhD, william.hanes@stonybrook.edu.
Program was made possible with the generous support of the NIH-REACH program, NYSTAR, Stony Brook University, Cold Spring Harbor Laboratory, Brookhaven National Laboratory, Feinstein Institute for Medical Research, SUNY Research Foundation, and Empire State Development
[post_title] => Funding Opportunity: Development and Commercialization of Bio-Based Technologies for Human Health and National Health Security
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Still time to register! Registration for the 8th annual Hack@CEWIT will close March 1 at 3pm.
Join hundreds of student hackers at the Center of Excellence in Wireless and Information Technology (CEWIT) for a 40-hour hackathon to learn new skills, make new connections, develop innovative ideas and compete for amazing prizes.
CEWIT will open its doors for the event at 5pm today. Do not miss your opportunity to Unleash Innovation and Transform Tomorrow
All participants must reside in the U.S and be currently registered in a college/university as an undergraduate, graduate, or PhD student.
Join Stony Brook University’s Intellectual Property Partners on Thursday, October 12, from 4:30 pm to 6 pm at the Charles B. Wang Center at Stony Brook University for the panel discussion titled “Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing.”
The event will be hosted by Intellectual Property Partners (IPP), the SBU Chapter of the National Academy of Inventors (NAI), and the Manufacturing and Technology Resource Consortium (MTRC) and will be followed by a networking cocktail reception from 6 pm to 7 pm.
Moderated by Dr. James Hayward, President, CEO and Chairman of Applied DNA Sciences, panelists include: – Adrian Howansky, PhD, Clinical Medical Physicist, Department of Radiology, Stony Brook University Hospital – Doreen Swift, Senior Director, Embedded Software Engineering, IPS – Michael R. Bielski, President, DevTech Partners – Nariman Boyle, MD, Director, Ophthalmic Plastic Orbit and Reconstructive Surgery, Department of Ophthalmology, Renaissance School of Medicine, Stony Brook University – Paul Schwartz, Director, Advanced Propulsion Technologies
This event is free and open to Stony Brook University attendees. Space is limited and registration is required. Register here to secure your spot.
