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Long Island Bioscience Hub Announces Funded Projects

December 7, 2015

Accelerating Biomedical Discoveries for Commercialization

STONY BROOK, N.Y. – December 7, 2015 – The Center for Biotechnology at Stony Brook University, on behalf of the Long Island Bioscience Hub (LIBH), announced today the recipients of the first technology development grants awarded by the Hub. Thirteen awards totaling $900,000 were granted to applicants from Stony Brook University, Cold Spring Harbor Laboratory, and Brookhaven National Laboratory.

The LIBH technology development grants are a multi-tiered funding initiative aimed at collectively contributing to a pipeline of commercially promising biomedical technology in the region. The three funding initiatives include Feasibility, Proof of Concept and Commercialization awards.

Feasibility awards are designed to rapidly test the feasibility of new ideas in a “fail-fast-or-proceed” format, or to add value to existing intellectual property leading to new market applications of an existing technology.  Proof of Concept Awards provide targeted, milestone driven support for proof of concept research, development, testing, and analysis of existing intellectual property. The final tier, Commercialization Awards, provide targeted, milestone-driven support for a subset of projects with existing intellectual property where additional investment will clearly advance the technology to a major value inflection point for commercialization.

The grants awarded this cycle will support technologies developed across multiple disciplines including pharmacology, biomedical engineering, chemistry, and microbiology. Among the award recipients were two post-doctoral researchers. Of the thirteen grants awarded, eight were Feasibility awards and five were Proof of Concept Awards. The recipients of this round of awards are:

Feasibility awards

  • Targeting Pathogenic Viral Infections with First-In-Class Viral Budding Inhibitors – Dr. Carol Carter
  • Development of Small Molecule Inhibitors for PLD6 as Therapeutics for Triple Negative Breast Cancer – Dr. Michael Frohman
  • Novel miR-129 Based Therapeutics for Colon Cancer – Dr. Jingfang Ju
  • Fast Hybrid Approach For Determination of Structure of Therapeutic Protein Complexes – Dr. Dima Kosakov
  • Enhancement of Protein Yields Using Mechanical Signals: Augmenting Biotech Production to Reduce Drug Costs – Dr. Gabriel Pagnotti
  • Non-invasive Acoustic Radiation Force Therapy for OA Induced Pain and Cartilage Regeneration – Dr. Yixian Qin
  • LDL as Biomarker for Childhood Tuberculosis (TB) – Dr. Xinxin Yang

Proof of Concept awards

  • A New Standard of Care for Implant Bed Preparation Utilizing an Innovative Drill Bit Technology – Dr. Marcous Abboud
  • Orthovoltage X-Ray Minibeams: Brain Tumor Therapy with Tissue-sparing Incident Beams – Dr. Avraham Dilmanian
  • NEW‐HARP: A Highly Sensitive Avalanche Selenium Detector for Time‐of‐Flight (TOF) Positron Emission Tomography (PET) – Dr. Amirhossein Goldan
  • Azasteroids for Combination Anti-TB Therapy – Dr. Nicole Sampson
  • A Novel Glioblastoma Drug – Oncolytic Virus PV1-Mono-Cre – Dr. Eckard Wimmer

​“We are excited to see such a robust and diverse portfolio of early stage technologies supported through the LIBH and NIH-REACH consortium,” said Clinton T. Rubin, Ph.D., Distinguished Professor, Chair, Department of Biomedical Engineering, and Director, Center for Biotechnology. “We are hopeful that this investment by the federal and state government, as well as SBU, CSHL and BNL, will foster and accelerate the translation of these technologies from the bench to the bed side, and help attract further investment from the industrial and financial sectors.”

The main goal of the LIBH is to foster the development of therapeutics, preventatives, diagnostics, devices and research tools emerging from LIBH partner institutions that address diseases within the NIH’s mission.

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                    [post_content] => 

Applications are now open for the 12th BioREACH Award Program from the Center for Biotechnology, which provides $50,000 in translational research funding for Stony Brook faculty and postdoctoral researchers to generate the evidence needed to advance promising innovations to the next stage of development.





BioREACH funds milestone-driven studies and welcomes biomedical innovations as well as platforms, tools, computational technologies, and other enabling technologies with the potential to contribute to solutions addressing unmet needs in health.





Application deadline: October 29, 2026, 5:00pm ET





For info sessions, eligibility and deadlines visit our REACH Website and FAQ.





The Center for Biotechnology (CfB) has helped advance some of Stony Brook University’s most impactful biomedical innovations, among them the yeast two-hybrid system, Xiaflex®, ReoPro®, Oracea®, and 3D virtual colonoscopy. The CfB has supported more than 475 faculty-led translational research projects and contributed to 306 license agreements generating $51 million in royalty returns to the University.





Questions? Reach out to our program contacts or sign up for office hours:





Dee Dao, PhD, Associate Director, dee.dao@stonybrook.edu
Office Hours: Monday–Friday, 2–3:30 PM | Sign up Here





Zelda Mendelowitz, PhD, Venture Associate, zelda.mendelowitz@stonybrook.edu
Office Hours: Tuesday, Wednesday, Friday, 8–11 AM | Sign up Here












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                    [post_content] => The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Program recently hosted a webinar to assist interested applicants with understanding proposal preparation, federal guidelines and resources, the funding process, and address general concerns.

The webinar presentation, recording, and transcript are now available (via web and attachments) for your reference. (Please be advised, an automated transcription service was used, and there may be grammatical errors and typos in the transcript.) We have done our best to correct as many errors as possible, but you are encouraged to reach out to us by email at sbir@od.nih.gov if anything remains unclear.
- Webinar Slides
- Recording
- Transcript

HHS SBIR and STTR Omnibus grant solicitations permit researcher-initiated topics around health, medicine and life science to be submitted for funding consideration. With any specific idea, you should speak directly with a HHS SBIR/STTR program manager at least a month BEFORE the deadline to gauge their interest.

You can find the HHS SBIR/STTR Omnibus Solicitations, and all of other SBIR/STTR solicitations on the Funding page of the SBIR/STTR Website: https://sbir.nih.gov/funding.

Be sure to also check the targeted funding announcements page, https://sbir.nih.gov/funding/individual-announcements. NIH Institutes and Centers will issue targeted SBIR/STTR grant solicitations around specific, high-priority research areas.

The next submission deadline is September 5, 2019.
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                    [post_content] => Stony Brook University Happenings recently profiled the Center for Biotechnology's designation as on of eight national accelerators under the Department of Health and Human Services’ (HHS) Biomedical Advanced Research and Development Authority (BARDA) Division of Research, Innovation and Ventures (DRIVe).  Excerpt below, read the full article here.

Sepsis occurs when chemicals released into the bloodstream to fight an infection trigger inflammatory responses throughout the body. It’s dangerous and often deadly. According to the U.S. Department of Health and Human Services, more than 250,000 people die from sepsis each year, and it is a leading cause of hospitalization in the U.S.

What if a simple test could identify the onset of sepsis as soon as it occurs? Better yet, what if wearable technology was available to alert doctors about sepsis in a patient before they ever show symptoms?

This may be possible in the future thanks to Stony Brook University’s participation in the federal government’s new BARDA-DRIVe initiative.

[caption id="attachment_3007" align="alignleft" width="300"] Stony Brook, NY; Stony Brook University: Center for Biotechnology's (CFB) Director of Operations Diane Fabel talks with Alyssa Tuthill, Instructional Support Associate/Biomedical Engineering Labs Manager while Graduate Research Assistant Vaughn Greene works with samples.[/caption]

The initiative, launched by the Division of Research, Innovation and Ventures (DRIVe), will be overseen by the Department of Health and Human Services’ (HHS) Biomedical Advanced Research and Development Authority (BARDA).

BARDA has selected Stony Brook’s Center for Biotechnology as one of eight national accelerators across the country to assist in scouting faculty innovators and businesses that are developing health security technology that meets the program’s goals. The initiative plans to focus first on sepsis and the early detection and diagnosis of infections that threaten national health. More goals will be identified over time. 

“National health security is essential for optimum public health, enabling our society to thrive,” said Stony Brook University President Samuel L. Stanley Jr. President Stanley is a biomedical researcher who specializes in emerging infectious diseases. He also chairs the Innovation Committee for the Long Island Regional Economic Development Council.

“With a proven record of research, discovery, innovation and product-development in the biomedical sciences, Stony Brook’s Center for Biotechnology is poised to become an important contributor to the BARDA-DRIVe initiative,” he said. “I am certain that the Center will advance and accelerate research discovery, and strategically collaborate with biotech companies to find solutions to better manage sepsis and emerging national health issues.”
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                    [post_content] => The Center for Biotechnology will be hosting our annual SBIR/STTR NIH Focused Workshop on January 15-16, 2019.

Did you know that the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) SBIR/STTR programs award over $2.6 billion in high-risk, non-diluted R&D funding annually to qualified small businesses?

Learn more about SBIR/STTR funding at this 1.5-day session focused on the National Institutes of Health (NIH) which will cover program essentials and how to compete for funding. Training will include:
– Current information on the SBIR/STTR programs
– Strategies for targeting your proposal to address the mission and requirements of the NIH
– How to approach each section of your proposal
– Planning your commercialization strategy
– Writing to meet the reviewers’ expectations

Tuesday, January 15, 2019, 8:30am – 4:30pm
Wednesday, January 17, 2019, 8:30am –12:00pm

Location: Long Island High Technology Incubator
Main Conference Room
25 Health Sciences Drive
Stony Brook, NY 11794

Registration Fee: $60 | Space is Limited. Pre-registration is required.
REGISTER ONLINE
                    [post_title] => SBIR/STTR INTENSIVE WORKSHOP: NIH FOCUSED
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            [post_content] => 

Applications are now open for the 12th BioREACH Award Program from the Center for Biotechnology, which provides $50,000 in translational research funding for Stony Brook faculty and postdoctoral researchers to generate the evidence needed to advance promising innovations to the next stage of development.





BioREACH funds milestone-driven studies and welcomes biomedical innovations as well as platforms, tools, computational technologies, and other enabling technologies with the potential to contribute to solutions addressing unmet needs in health.





Application deadline: October 29, 2026, 5:00pm ET





For info sessions, eligibility and deadlines visit our REACH Website and FAQ.





The Center for Biotechnology (CfB) has helped advance some of Stony Brook University’s most impactful biomedical innovations, among them the yeast two-hybrid system, Xiaflex®, ReoPro®, Oracea®, and 3D virtual colonoscopy. The CfB has supported more than 475 faculty-led translational research projects and contributed to 306 license agreements generating $51 million in royalty returns to the University.





Questions? Reach out to our program contacts or sign up for office hours:





Dee Dao, PhD, Associate Director, dee.dao@stonybrook.edu
Office Hours: Monday–Friday, 2–3:30 PM | Sign up Here





Zelda Mendelowitz, PhD, Venture Associate, zelda.mendelowitz@stonybrook.edu
Office Hours: Tuesday, Wednesday, Friday, 8–11 AM | Sign up Here












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