Back to News & Events

CFB Client Secures $3M Public and Private Investment

Codagenix, Inc., a clinical stage, venture and public-sector-funded small business, announced it has secured an additional $3M in funding in support of its live-attenuated Respiratory Syncytial Virus (RSV) vaccine candidate that was developed in collaboration with National Institute of Allergy and Infectious Diseases (NIAID), a part of NIH.

The public funding to Codagenix is via a Phase II SBIR grant for $1.5M to support the pre-clinical manufacturing of the vaccine candidate. The private funding of $1.5M was provided by TopSpin Partners to support a Phase I trial to demonstrate safety and immunogenicity in aged volunteers. The two funding source were not linked; however, both are dedicated to supporting Codagneix’s RSV vaccine through a Phase I trial. Clinical Trial material of Codagenix RSV Vaccine candidate is currently being manufactured with a Phase I targeted for Q3- or Q4-2018.

“Codagenix is an incredible example of a company rooting in our expanding bioecosystem, growing from a startup out of Stony Brook University into a clinical stage company” stated Dr. Clinton Rubin, Director of the New York State Center for Biotechnology at Stony Brook University. “The Center for Biotechnology is proud to provide ongoing support for the work they are doing through our various programs including the Applied Research and Development awards and the Long Island Bioscience Hub funding initiatives.

“We are wrapping up a Phase I with our live-attenuated Influenza Vaccine in Q1-2018 and are very much looking forward to adding a second clinical-stage compound to our pipeline with RSV,” stated Codegenix COO J. Robert Coleman. “We are grateful to our investors and partners like the Center for Biotechnology that understand our vision and continually support our development at these early stages. We are demonstrating that our platform provides a rational means to design vaccines against a range targets – yielding candidates suitable for full clinical development.”

Codagenix has raised a total of $10M since 2015 – with its influenza vaccine candidate currently in Phase I and a pre-clinical pipeline that includes Zika, Dengue, and Agricultural targets in addition to RSV.

RSV is a virus that targets newborns and the elderly, with an estimated market size of $2 Billion for a potential RSV vaccine.

About Codagenix Inc.
Codagenix Inc., a biotechnology company on Long Island, New York, is developing live attenuated vaccines using a “disruptive” software-based rational design algorithm that is unlike previous vaccine “platforms”. By leveraging the redundancy in the genetic code (various codons exist at the gene level to encode the same amino acid at the protein level), the Codagenix algorithm re-structures viral genomes into a sub-optimal genetic code. The so-called “deoptimized” viruses have resulted in highly attenuated vaccine strains that are effective at greatly reduced doses, because they present every antigen of the pathogen, while being 100% identical to the target pathogen at the protein level. The Codagenix pipeline of vaccines includes Influenza, respiratory syncytial virus (RSV), Zika, Dengue, foot-and-mouth disease virus (FMDV), pathogenic E. coli, and other pathogens.

Codagenix has also been supported the Center for Biotechnology at Stony brook University which is a New York State Center for Advanced Technology and NIH-designated Research, Evaluation and Commercialization Hub (REACH)

Related Stories

WP_Query Object
(
    [query] => Array
        (
            [post_type] => post
            [posts_per_page] => 3
            [post_status] => publish
            [orderby] => rand
        )

    [query_vars] => Array
        (
            [post_type] => post
            [posts_per_page] => 3
            [post_status] => publish
            [orderby] => rand
            [error] => 
            [m] => 
            [p] => 0
            [post_parent] => 
            [subpost] => 
            [subpost_id] => 
            [attachment] => 
            [attachment_id] => 0
            [name] => 
            [pagename] => 
            [page_id] => 0
            [second] => 
            [minute] => 
            [hour] => 
            [day] => 0
            [monthnum] => 0
            [year] => 0
            [w] => 0
            [category_name] => 
            [tag] => 
            [cat] => 
            [tag_id] => 
            [author] => 
            [author_name] => 
            [feed] => 
            [tb] => 
            [paged] => 0
            [meta_key] => 
            [meta_value] => 
            [preview] => 
            [s] => 
            [sentence] => 
            [title] => 
            [fields] => 
            [menu_order] => 
            [embed] => 
            [category__in] => Array
                (
                )

            [category__not_in] => Array
                (
                )

            [category__and] => Array
                (
                )

            [post__in] => Array
                (
                )

            [post__not_in] => Array
                (
                )

            [post_name__in] => Array
                (
                )

            [tag__in] => Array
                (
                )

            [tag__not_in] => Array
                (
                )

            [tag__and] => Array
                (
                )

            [tag_slug__in] => Array
                (
                )

            [tag_slug__and] => Array
                (
                )

            [post_parent__in] => Array
                (
                )

            [post_parent__not_in] => Array
                (
                )

            [author__in] => Array
                (
                )

            [author__not_in] => Array
                (
                )

            [search_columns] => Array
                (
                )

            [ignore_sticky_posts] => 
            [suppress_filters] => 
            [cache_results] => 1
            [update_post_term_cache] => 1
            [update_menu_item_cache] => 
            [lazy_load_term_meta] => 1
            [update_post_meta_cache] => 1
            [nopaging] => 
            [comments_per_page] => 50
            [no_found_rows] => 
            [order] => 
        )

    [tax_query] => WP_Tax_Query Object
        (
            [queries] => Array
                (
                )

            [relation] => AND
            [table_aliases:protected] => Array
                (
                )

            [queried_terms] => Array
                (
                )

            [primary_table] => wp_posts
            [primary_id_column] => ID
        )

    [meta_query] => WP_Meta_Query Object
        (
            [queries] => Array
                (
                )

            [relation] => 
            [meta_table] => 
            [meta_id_column] => 
            [primary_table] => 
            [primary_id_column] => 
            [table_aliases:protected] => Array
                (
                )

            [clauses:protected] => Array
                (
                )

            [has_or_relation:protected] => 
        )

    [date_query] => 
    [request] => 
					SELECT SQL_CALC_FOUND_ROWS  wp_posts.ID
					FROM wp_posts 
					WHERE 1=1  AND wp_posts.post_type = 'post' AND ((wp_posts.post_status = 'publish'))
					
					ORDER BY RAND()
					LIMIT 0, 3
				
    [posts] => Array
        (
            [0] => WP_Post Object
                (
                    [ID] => 4285
                    [post_author] => 4
                    [post_date] => 2023-09-11 12:13:16
                    [post_date_gmt] => 2023-09-11 16:13:16
                    [post_content] => 

Join Stony Brook University’s Intellectual Property Partners on Thursday, October 12, from 4:30 pm to 6 pm at the Charles B. Wang Center at Stony Brook University for the panel discussion titled “Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing.”

The event will be hosted by Intellectual Property Partners (IPP), the SBU Chapter of the National Academy of Inventors (NAI), and the Manufacturing and Technology Resource Consortium (MTRC) and will be followed by a networking cocktail reception from 6 pm to 7 pm.

Moderated by Dr. James Hayward, President, CEO and Chairman of Applied DNA Sciences, panelists include:
– Adrian Howansky, PhD, Clinical Medical Physicist, Department of Radiology, Stony Brook University Hospital
– Doreen Swift, Senior Director, Embedded Software Engineering, IPS
– Michael R. Bielski, President, DevTech Partners
– Nariman Boyle, MD, Director, Ophthalmic Plastic Orbit and Reconstructive Surgery, Department of Ophthalmology, Renaissance School of Medicine, Stony Brook University
– Paul Schwartz, Director, Advanced Propulsion Technologies

This event is free and open to Stony Brook University attendees. Space is limited and registration is required. Register here to secure your spot.

For more information visit: https://www.stonybrook.edu/commcms/ipp/Events/Manufacturing.php

[post_title] => "Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing" 10/12/23 [post_excerpt] => Join Stony Brook University’s Intellectual Property Partners on October 12th for the panel discussion titled “Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing.” [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => bring-your-new-technology-innovations-to-life-through-prototyping-and-manufacturing-10-12-23 [to_ping] => [pinged] => [post_modified] => 2023-11-15 11:24:35 [post_modified_gmt] => 2023-11-15 16:24:35 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=4285 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [1] => WP_Post Object ( [ID] => 3269 [post_author] => 3 [post_date] => 2019-06-10 15:25:24 [post_date_gmt] => 2019-06-10 15:25:24 [post_content] => The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Program recently hosted a webinar to assist interested applicants with understanding proposal preparation, federal guidelines and resources, the funding process, and address general concerns. The webinar presentation, recording, and transcript are now available (via web and attachments) for your reference. (Please be advised, an automated transcription service was used, and there may be grammatical errors and typos in the transcript.) We have done our best to correct as many errors as possible, but you are encouraged to reach out to us by email at sbir@od.nih.gov if anything remains unclear. - Webinar SlidesRecording - Transcript HHS SBIR and STTR Omnibus grant solicitations permit researcher-initiated topics around health, medicine and life science to be submitted for funding consideration. With any specific idea, you should speak directly with a HHS SBIR/STTR program manager at least a month BEFORE the deadline to gauge their interest. You can find the HHS SBIR/STTR Omnibus Solicitations, and all of other SBIR/STTR solicitations on the Funding page of the SBIR/STTR Website: https://sbir.nih.gov/funding. Be sure to also check the targeted funding announcements page, https://sbir.nih.gov/funding/individual-announcements. NIH Institutes and Centers will issue targeted SBIR/STTR grant solicitations around specific, high-priority research areas. The next submission deadline is September 5, 2019. [post_title] => SBIR/STTR Omnibus Webinar Recording, Transcript, and Slides Available [post_excerpt] => [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => sbirsttr-omnibus-webinar-recording-transcript-and-slides-available [to_ping] => [pinged] => [post_modified] => 2019-06-10 15:25:24 [post_modified_gmt] => 2019-06-10 15:25:24 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=3269 [menu_order] => 94 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 3228 [post_author] => 3 [post_date] => 2019-04-08 14:42:13 [post_date_gmt] => 2019-04-08 14:42:13 [post_content] => Thinking of starting a life science company? The Center for Biotechnology can provide access to a compelling, pre-screened pipeline of academic technologies, milestone based incentives, access to early-stage funding opportunities, and staff support to serve as your virtual start-up team. The Long Island, NY region has a well demonstrated capacity for innovation, serving as home to Cold Spring Harbor Laboratory, Stony Brook University, the Feinstein Institute at Northwell Health, and Brookhaven National Laboratory, among others. Sample technologies that have emerged from the region include Magnetic Resonance Imaging (MRI), ReoPro®; Xiaflex®; Cavistat®; Oracea®, and 3D Virtual Colonoscopy. More details on the BioEntrepreneur-in-Residence initiative can be found here. Women and underrepresented minorities are encouraged to inquire. If you are interested in the initiative or would like to discuss further, please contact Diane Fabel at diane.fabel@stonybrook.edu or call 631.632.1582. [post_title] => Call for Entrepreneurs! [post_excerpt] => If you are taking the entrepreneurial leap for the first time, or are a seasoned entrepreneur looking for their next venture, the Center for Biotechnology would like to hear from you. [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => call-for-entrepreneurs [to_ping] => [pinged] => https://centerforbiotechnology.org/what-we-do/business-development/ [post_modified] => 2019-05-03 16:38:03 [post_modified_gmt] => 2019-05-03 16:38:03 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=3228 [menu_order] => 97 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 2552 [post_author] => 3 [post_date] => 2017-01-09 15:31:38 [post_date_gmt] => 2017-01-09 15:31:38 [post_content] => Sincerest congratulations to our clients who are being recognized among Stony Brook University's 40 under 40 for 2016.  Since earning their Stony Brook degree, they have gone on to pursue their passions, help others and lead positive change. J. Robert Coleman ’08, PhD Molecular Genetics and Microbiology - Chief Operating Officer, Codagenix, Inc Katarzyna M. Sawicka ’04, ’05, ’14, BS Engineering Chemistry, MS Chemistry, PhD Biomedical Engineering - Founder and President, ImmunoMatrix Joseph Scaduto ’08, MBA Business Administration - Founder and CEO, Traverse Biosciences Inc.
libn40-40Additionally, warmest wishes of continued success to Stony Brook's Director of Government Relations, Lauren Brookmeyer, who was recently named a Long Island Business News "40 under 40 Class of 2017" honoree.   [post_title] => Congratulations 40 under 40 Winners! [post_excerpt] => Three Center for Biotech clients are among the talented individuals recognized as Stony Brook University 's 2016 "40 under 40". [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => congratulations-40-under-40-winners [to_ping] => [pinged] => [post_modified] => 2017-01-09 15:31:38 [post_modified_gmt] => 2017-01-09 15:31:38 [post_content_filtered] => [post_parent] => 0 [guid] => http://centerforbiotechnology.org/?p=2552 [menu_order] => 155 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) ) [post_count] => 4 [current_post] => -1 [before_loop] => 1 [in_the_loop] => [post] => WP_Post Object ( [ID] => 4285 [post_author] => 4 [post_date] => 2023-09-11 12:13:16 [post_date_gmt] => 2023-09-11 16:13:16 [post_content] =>

Join Stony Brook University’s Intellectual Property Partners on Thursday, October 12, from 4:30 pm to 6 pm at the Charles B. Wang Center at Stony Brook University for the panel discussion titled “Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing.”

The event will be hosted by Intellectual Property Partners (IPP), the SBU Chapter of the National Academy of Inventors (NAI), and the Manufacturing and Technology Resource Consortium (MTRC) and will be followed by a networking cocktail reception from 6 pm to 7 pm.

Moderated by Dr. James Hayward, President, CEO and Chairman of Applied DNA Sciences, panelists include:
– Adrian Howansky, PhD, Clinical Medical Physicist, Department of Radiology, Stony Brook University Hospital
– Doreen Swift, Senior Director, Embedded Software Engineering, IPS
– Michael R. Bielski, President, DevTech Partners
– Nariman Boyle, MD, Director, Ophthalmic Plastic Orbit and Reconstructive Surgery, Department of Ophthalmology, Renaissance School of Medicine, Stony Brook University
– Paul Schwartz, Director, Advanced Propulsion Technologies

This event is free and open to Stony Brook University attendees. Space is limited and registration is required. Register here to secure your spot.

For more information visit: https://www.stonybrook.edu/commcms/ipp/Events/Manufacturing.php

[post_title] => "Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing" 10/12/23 [post_excerpt] => Join Stony Brook University’s Intellectual Property Partners on October 12th for the panel discussion titled “Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing.” [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => bring-your-new-technology-innovations-to-life-through-prototyping-and-manufacturing-10-12-23 [to_ping] => [pinged] => [post_modified] => 2023-11-15 11:24:35 [post_modified_gmt] => 2023-11-15 16:24:35 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=4285 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [comment_count] => 0 [current_comment] => -1 [found_posts] => 249 [max_num_pages] => 83 [max_num_comment_pages] => 0 [is_single] => [is_preview] => [is_page] => [is_archive] => [is_date] => [is_year] => [is_month] => [is_day] => [is_time] => [is_author] => [is_category] => [is_tag] => [is_tax] => [is_search] => [is_feed] => [is_comment_feed] => [is_trackback] => [is_home] => 1 [is_privacy_policy] => [is_404] => [is_embed] => [is_paged] => [is_admin] => [is_attachment] => [is_singular] => [is_robots] => [is_favicon] => [is_posts_page] => [is_post_type_archive] => [query_vars_hash:WP_Query:private] => 325c4f9f1aebaa5ec90666fa54175ba0 [query_vars_changed:WP_Query:private] => [thumbnails_cached] => [allow_query_attachment_by_filename:protected] => [stopwords:WP_Query:private] => [compat_fields:WP_Query:private] => Array ( [0] => query_vars_hash [1] => query_vars_changed ) [compat_methods:WP_Query:private] => Array ( [0] => init_query_flags [1] => parse_tax_query ) )

“Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing” 10/12/23

More Information

SBIR/STTR Omnibus Webinar Recording, Transcript, and Slides Available

More Information

Call for Entrepreneurs!

More Information

Congratulations 40 under 40 Winners!

More Information