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CFB BEIR Receives $1.9M SBIR Fast-Track

Avanti Biosciences, Inc. a preclinical-stage biopharmaceutical company lead by Center for Biotechnology BioEntrepreneur-in-Residence Dr. Gian Luca Araldi, has announced that the National Institute of Aging (NIA) has awarded the Company an SBIR fast-track grant of up to $1,930,000 to support the company’s small molecule treatment for Alzheimer’s disease (AD) over the next 3 years.

The award will enable the preparation and testing of Avanti’s proprietary compounds derivatized from natural catechins, which inhibit DYRK1A, an enzyme that modulates tau phosphorylation. Working with NY Institute for Basic Research and the University of California San Diego (UCSD), the company hopes to attenuate and potentially reverse pathogenesis for Alzheimer’s disease and other neurodegenerative diseases.

“This award marks a significant milestone for Avanti Biosciences and an important step for their research into a treatment for Alzheimer’s disease” stated Dr. Clinton Rubin, Director of the New York State Center for Biotechnology at Stony Brook University. “The Center for Biotechnology is thrilled to see another success for one of the emerging bioscience companies fueling our regional bioecosystem and we proudly support Dr. Araldi’s work as one of our BioEntrepreneurs-in-Residence.”

Dr. Gian Luca Araldi, Founder and Chief Executive Officer of Avanti, stated, “We are delighted to have been granted this funding from the NIA as it underscores the great need for innovative, effective treatments for this disease, and recognizes the potential benefits that our compounds may provide for patients with AD. The continuous support of Center for Biotechnology and the BioEntrepreneur-in-Residence program has been critical force in the development of our technology and the company as whole.”

More than five million people in the United States are living with Alzheimer’s disease, a progressive, irreversible, neurodegenerative disease that destroys memory and other cognitive abilities. It is the sixth leading cause of death in the United States and as the aging population in the country grows, the incidence rate is expected to rise dramatically.

Learn more about Avanti Biosciences: avantibiosciences.com

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Join Stony Brook University’s Intellectual Property Partners on Thursday, October 12, from 4:30 pm to 6 pm at the Charles B. Wang Center at Stony Brook University for the panel discussion titled “Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing.”

The event will be hosted by Intellectual Property Partners (IPP), the SBU Chapter of the National Academy of Inventors (NAI), and the Manufacturing and Technology Resource Consortium (MTRC) and will be followed by a networking cocktail reception from 6 pm to 7 pm.

Moderated by Dr. James Hayward, President, CEO and Chairman of Applied DNA Sciences, panelists include:
– Adrian Howansky, PhD, Clinical Medical Physicist, Department of Radiology, Stony Brook University Hospital
– Doreen Swift, Senior Director, Embedded Software Engineering, IPS
– Michael R. Bielski, President, DevTech Partners
– Nariman Boyle, MD, Director, Ophthalmic Plastic Orbit and Reconstructive Surgery, Department of Ophthalmology, Renaissance School of Medicine, Stony Brook University
– Paul Schwartz, Director, Advanced Propulsion Technologies

This event is free and open to Stony Brook University attendees. Space is limited and registration is required. Register here to secure your spot.

For more information visit: https://www.stonybrook.edu/commcms/ipp/Events/Manufacturing.php

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Kathera Bioscience Inc., a privately-held biotech startup was awarded a SBIR Fast Track grant with a value of up to $3,298,530 from the National Institute of Allergy and Infectious Diseases (NIAID) for its dihydrofolate reductase (DHFR) program. Kathera Bioscience was founded by CFB Advisor and Long Island BIoMentor Initiative Mentor Dr. Stephen Parent.

Kathera is developing novel therapeutics to treat fungal infections, a major cause of human disease with an estimated 11.5 million annual life-threatening infections globally, resulting in more than 1.5 million deaths. The award will fund selection of a lead series in the Phase 1 award and lead optimization in Phase 2. Read more about Kathera and the award here.

[post_title] => Kathera Bioscience Receives SBIR Phase I Fast Track Award To Advance Novel Drugs To Treat Life Threatening Fungal Infections [post_excerpt] => Kathera Bioscience Inc.,founded by CFB Advisor and Long Island BIoMentor Initiative Mentor Dr. Stephen Parent, was awarded a SBIR Fast Track grant with a value of up to $3,298,530. [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => kathera-phase2-2024 [to_ping] => [pinged] => [post_modified] => 2024-02-19 10:25:46 [post_modified_gmt] => 2024-02-19 15:25:46 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=4380 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 2621 [post_author] => 3 [post_date] => 2017-03-20 13:58:38 [post_date_gmt] => 2017-03-20 13:58:38 [post_content] => CEWIT, the Center for Biotechnology and Henry Schein, Inc., have joined forces to host an expert symposium presenting cutting-edge advances in biomedical and clinical-related technologies, digital health, and smart medical devices, focusing on the technology as well as the joint industry, academic, and R&D partnerships that are integral to major innovations in the healthtech domain — at Stony Brook University. Tuesday, March 28, 2017, 9:30am-3:30pm The Center of Excellence in Wireless and Information Technology (CEWIT) at Stony Brook University 1500 Stony Brook Road, Stony Brook, NY 11794-6040 Event is free but registration is requires. View full agenda and register here: www.cewit.org/events/healthtech.html [post_title] => CEWIT Medical Technologies and Healthcare Innovations Symposium [post_excerpt] => Featuring cutting-edge advances in biomedical and clinical-related technologies, digital health, and smart medical devices, focusing on the technology as well as the joint industry, academic, and R&D partnerships that are integral to major innovations in the healthtech domain — at Stony Brook University. [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => cewit-medical-technologies-and-healthcare-innovations-symposium [to_ping] => [pinged] => [post_modified] => 2017-03-20 13:59:29 [post_modified_gmt] => 2017-03-20 13:59:29 [post_content_filtered] => [post_parent] => 0 [guid] => http://centerforbiotechnology.org/?p=2621 [menu_order] => 151 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 3954 [post_author] => 4 [post_date] => 2022-11-08 14:56:08 [post_date_gmt] => 2022-11-08 14:56:08 [post_content] =>

Apply for the first cohort of FY2023 by Nov. 16!

The I-Corps™ at NIH Program helps current Phase I SBIR/STTR awardees from the NIH and CDC transition from researcher to entrepreneur.

This 8.5-week training program provides practical guidance from experienced industry professionals that will move you forward on your path toward commercialization. Past participants have written strong SBIR/STTR Phase II applications, won partnerships and investments, and built vast networks in the field.

Apply for the first cohort of FY2023 through the NIH ASSIST platform by 5:00 p.m. your local time on Wednesday, November 16.

Questions? Review the FAQs or contact us if you need help at icorps@mail.nih.gov.

Learn More and Apply: https://sbir.cancer.gov/commercialization/business/icorps

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Join Stony Brook University’s Intellectual Property Partners on Thursday, October 12, from 4:30 pm to 6 pm at the Charles B. Wang Center at Stony Brook University for the panel discussion titled “Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing.”

The event will be hosted by Intellectual Property Partners (IPP), the SBU Chapter of the National Academy of Inventors (NAI), and the Manufacturing and Technology Resource Consortium (MTRC) and will be followed by a networking cocktail reception from 6 pm to 7 pm.

Moderated by Dr. James Hayward, President, CEO and Chairman of Applied DNA Sciences, panelists include:
– Adrian Howansky, PhD, Clinical Medical Physicist, Department of Radiology, Stony Brook University Hospital
– Doreen Swift, Senior Director, Embedded Software Engineering, IPS
– Michael R. Bielski, President, DevTech Partners
– Nariman Boyle, MD, Director, Ophthalmic Plastic Orbit and Reconstructive Surgery, Department of Ophthalmology, Renaissance School of Medicine, Stony Brook University
– Paul Schwartz, Director, Advanced Propulsion Technologies

This event is free and open to Stony Brook University attendees. Space is limited and registration is required. Register here to secure your spot.

For more information visit: https://www.stonybrook.edu/commcms/ipp/Events/Manufacturing.php

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“Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing” 10/12/23

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NIH iCorps: Apply by Nov. 16

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