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BARDA RFI/CALL for Technologies

BARDA DRIVe is seeking information on technologies that are relevant to AI for automated biomedical image acquisition and AI for automated biomedical image interpretation, with a focus on reducing the burden on clinical, technician, and care staff in any setting. If you can provide insight on any of the items listed below, please contact Phuong Nguyen (phuong.t.nguyen@stonybrook.edu) by June 8, 2021.

This request encompass all stages of development from early research/academic labs through start up and late commercialization: They are more interested in technical rather than any particular stage of development, thus the focus is not just on the commercial sector but also on the work being conducted at academic/research/medical/FFRDC organizations. This can be an AI solution applied to existing imaging infrastructure, or new imaging devices. This AI and imaging combination should provide new value propositions, form factors, or use cases that are only possible with integration of AI.

Specific areas and use cases of interest include but are not limited to:
– Automated biomedical image interpretation, primarily in ultrasound, computer tomography, and magnetic resonance imaging.
– Approaches to automated interpretation of optical and x-ray images are of interest, but of secondary priority.
– AI-based diagnostic image acquisition and image interpretation in emergency medical services (EMSs) and in surgical settings to accurately assess the severity of a patient’s medical condition, e.g. the location of an internal hemorrhage or the location of a broken bone, torn ligament or other injury.
– AI-based automated image reconstruction.
– AI-based automated analysis of cancer screening images (e.g. mammograms)
– AI-assisted image guidance for placement of medical devices, e.g. catheterization
– AI-assisted fluoroscopy

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CFB Client, IAMBIC has been awarded approximately $1M in grant funding from the National Science Foundation Small Business Innovation Research program. IAMBIC is an innovative shoe company disrupting the centuries-old footwear industry with their sizeless, precision-fit footwear driven by proprietary AI algorithms. This substantial funding from NSF enables IAMBIC to scale its cutting-edge precision-fit shoe design and manufacturing.

The Center for Biotechnology and its accelerator programs have been instrumental in assisting IAMBIC with their SBIR pursuits and commercialization development.

Read more about IAMBIC and their recent funding here.

[post_title] => CFB Client IAMBIC Receives $1 Million NSF SBIR Phase II Grant [post_excerpt] => This substantial funding from NSF enables IAMBIC to scale its operations. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => iambic-receives-1-million-nsf-sbir-phase-ii-grant [to_ping] => [pinged] => [post_modified] => 2024-11-19 10:50:15 [post_modified_gmt] => 2024-11-19 15:50:15 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=4439 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [1] => WP_Post Object ( [ID] => 2889 [post_author] => 3 [post_date] => 2017-12-01 20:57:05 [post_date_gmt] => 2017-12-01 20:57:05 [post_content] => Date: May 9, 10, 11, 2018 Accepting Applications: December 15, 2017 – Seating will be limited. Unlocking the power of female leaders for a competitive and innovative future in STEM Occupations in the fields of science, technology, engineering and mathematics are expected to continue to outpace non-STEM jobs over the next decade. Yet while women make up more than half of all workers with post-secondary degrees, only slightly more than a quarter of them are in core STEM fields. The Women in STEM Leadership Program encourages and equips women at all stages of their careers with the skills necessary to advance as productive and valuable employees in their chosen STEM fields. Call 1-631-216-7518 or fill out the form below for detailed program information: Learn more & apply here. [post_title] => Women in STEM Leadership Program [post_excerpt] => [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => 2889-2 [to_ping] => [pinged] => [post_modified] => 2018-01-25 15:43:58 [post_modified_gmt] => 2018-01-25 15:43:58 [post_content_filtered] => [post_parent] => 0 [guid] => http://centerforbiotechnology.org/?p=2889 [menu_order] => 133 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 2064 [post_author] => 3 [post_date] => 2015-12-07 20:15:00 [post_date_gmt] => 2015-12-07 20:15:00 [post_content] => Accelerating Biomedical Discoveries for Commercialization STONY BROOK, N.Y. – December 7, 2015 - The Center for Biotechnology at Stony Brook University, on behalf of the Long Island Bioscience Hub (LIBH), announced today the recipients of the first technology development grants awarded by the Hub. Thirteen awards totaling $900,000 were granted to applicants from Stony Brook University, Cold Spring Harbor Laboratory, and Brookhaven National Laboratory. The LIBH technology development grants are a multi-tiered funding initiative aimed at collectively contributing to a pipeline of commercially promising biomedical technology in the region. The three funding initiatives include Feasibility, Proof of Concept and Commercialization awards. Feasibility awards are designed to rapidly test the feasibility of new ideas in a “fail-fast-or-proceed” format, or to add value to existing intellectual property leading to new market applications of an existing technology.  Proof of Concept Awards provide targeted, milestone driven support for proof of concept research, development, testing, and analysis of existing intellectual property. The final tier, Commercialization Awards, provide targeted, milestone-driven support for a subset of projects with existing intellectual property where additional investment will clearly advance the technology to a major value inflection point for commercialization. The grants awarded this cycle will support technologies developed across multiple disciplines including pharmacology, biomedical engineering, chemistry, and microbiology. Among the award recipients were two post-doctoral researchers. Of the thirteen grants awarded, eight were Feasibility awards and five were Proof of Concept Awards. The recipients of this round of awards are: Feasibility awards
  • Targeting Pathogenic Viral Infections with First-In-Class Viral Budding Inhibitors - Dr. Carol Carter
  • Development of Small Molecule Inhibitors for PLD6 as Therapeutics for Triple Negative Breast Cancer - Dr. Michael Frohman
  • Novel miR-129 Based Therapeutics for Colon Cancer - Dr. Jingfang Ju
  • Fast Hybrid Approach For Determination of Structure of Therapeutic Protein Complexes - Dr. Dima Kosakov
  • Enhancement of Protein Yields Using Mechanical Signals: Augmenting Biotech Production to Reduce Drug Costs - Dr. Gabriel Pagnotti
  • Non-invasive Acoustic Radiation Force Therapy for OA Induced Pain and Cartilage Regeneration - Dr. Yixian Qin
  • LDL as Biomarker for Childhood Tuberculosis (TB) - Dr. Xinxin Yang
Proof of Concept awards
  • A New Standard of Care for Implant Bed Preparation Utilizing an Innovative Drill Bit Technology - Dr. Marcous Abboud
  • Orthovoltage X-Ray Minibeams: Brain Tumor Therapy with Tissue-sparing Incident Beams - Dr. Avraham Dilmanian
  • NEW‐HARP: A Highly Sensitive Avalanche Selenium Detector for Time‐of‐Flight (TOF) Positron Emission Tomography (PET) - Dr. Amirhossein Goldan
  • Azasteroids for Combination Anti-TB Therapy - Dr. Nicole Sampson
  • A Novel Glioblastoma Drug – Oncolytic Virus PV1-Mono-Cre - Dr. Eckard Wimmer
​“We are excited to see such a robust and diverse portfolio of early stage technologies supported through the LIBH and NIH-REACH consortium,” said Clinton T. Rubin, Ph.D., Distinguished Professor, Chair, Department of Biomedical Engineering, and Director, Center for Biotechnology. “We are hopeful that this investment by the federal and state government, as well as SBU, CSHL and BNL, will foster and accelerate the translation of these technologies from the bench to the bed side, and help attract further investment from the industrial and financial sectors.” The main goal of the LIBH is to foster the development of therapeutics, preventatives, diagnostics, devices and research tools emerging from LIBH partner institutions that address diseases within the NIH’s mission. [post_title] => Long Island Bioscience Hub Announces Funded Projects [post_excerpt] => [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => long-island-bioscience-hub-announces-funded-projects [to_ping] => [pinged] => [post_modified] => 2016-03-29 20:18:36 [post_modified_gmt] => 2016-03-29 20:18:36 [post_content_filtered] => [post_parent] => 0 [guid] => http://centerforbiotechnology.org/?p=2064 [menu_order] => 195 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 3181 [post_author] => 3 [post_date] => 2019-02-28 16:35:02 [post_date_gmt] => 2019-02-28 16:35:02 [post_content] => Center for Biotechnology Director Dr. Clinton Rubin has co-authored a recent article published in Nature Reviews Endocrinology "“Combating osteoporosis and obesity with exercise: leveraging cell mechanosensitivity”.  Abstract below, full article here. Abstract:  Osteoporosis, a condition of skeletal decline that undermines quality of life, is treated with pharmacological interventions that are associated with poor adherence and adverse effects. Complicating efforts to improve clinical outcomes, the incidence of obesity is increasing, predisposing the population to a range of musculoskeletal complications and metabolic disorders. Pharmacological management of obesity has yet to deliver notable reductions in weight and debilitating complications are rarely avoided. By contrast, exercise shows promise as a non-invasive and non-pharmacological method of regulating both osteoporosis and obesity. The principal components of exercise — mechanical signals — promote bone and muscle anabolism while limiting formation and expansion of fat mass. Mechanical regulation of bone and marrow fat might be achieved by regulating functions of differentiated cells in the skeletal tissue while biasing lineage selection of their common progenitors — mesenchymal stem cells. An inverse relationship between adipocyte versus osteoblast fate selection from stem cells is implicated in clinical conditions such as childhood obesity and increased marrow adiposity in type 2 diabetes mellitus, as well as contributing to skeletal frailty. Understanding how exercise-induced mechanical signals can be used to improve bone quality while decreasing fat mass and metabolic dysfunction should lead to new strategies to treat chronic diseases such as osteoporosis and obesity. [post_title] => “Combating osteoporosis and obesity with exercise: leveraging cell mechanosensitivity” [post_excerpt] => [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => combating-osteoporosis-and-obesity-with-exercise-leveraging-cell-mechanosensitivity [to_ping] => [pinged] => [post_modified] => 2019-04-09 14:40:26 [post_modified_gmt] => 2019-04-09 14:40:26 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=3181 [menu_order] => 100 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) ) [post_count] => 4 [current_post] => -1 [before_loop] => 1 [in_the_loop] => [post] => WP_Post Object ( [ID] => 4439 [post_author] => 3 [post_date] => 2024-07-30 15:29:07 [post_date_gmt] => 2024-07-30 19:29:07 [post_content] =>

CFB Client, IAMBIC has been awarded approximately $1M in grant funding from the National Science Foundation Small Business Innovation Research program. IAMBIC is an innovative shoe company disrupting the centuries-old footwear industry with their sizeless, precision-fit footwear driven by proprietary AI algorithms. This substantial funding from NSF enables IAMBIC to scale its cutting-edge precision-fit shoe design and manufacturing.

The Center for Biotechnology and its accelerator programs have been instrumental in assisting IAMBIC with their SBIR pursuits and commercialization development.

Read more about IAMBIC and their recent funding here.

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CFB Client IAMBIC Receives $1 Million NSF SBIR Phase II Grant

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Women in STEM Leadership Program

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Long Island Bioscience Hub Announces Funded Projects

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“Combating osteoporosis and obesity with exercise: leveraging cell mechanosensitivity”

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