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Annual Applied Research And Development Awards Announced

Awards Support Innovative Research Collaborations Between Academic Faculty and Regional Bioscience Companies

The Center for Biotechnology at Stony Brook University has announced the recipients of the 2017-2018 Applied Research & Development (ARAD) awards. The ARAD Program is designed to help bridge the gap between the early-stage technology discovery and development capabilities of the academic community, and the later-stage commercial development interests of the bioscience industry.

The program currently provides matching funds on a competitive basis to support collaborations between Stony Brook University faculty and New York State corporate partners in all areas of medical biotechnology. The primary interest is in supporting development of technologies that will help companies hit commercially relevant milestones, and that have the potential to positively impact the New York State economy.

Projects supported this year include the furthered development of an ICU temporary pacemaker, a novel Lymphoma treatment, a novel synthetic peptide based therapeutic for Osteoporosis, further development of an fMRI Dynamic Phantom, development of novel vaccines, third generation taxoid based nanomedicine for chemoresistant cancer, development of a polymeric heart valve, a drug delivery technology for treatment of gastrointestinal diseases, and the development of skin brightening agents.

“The Center’s Applied Research and Development Program speaks to the core of what our organization does – collaborate with New York State companies to help them develop commercially promising technologies that will lead to strategic partnerships, investment, corporate revenues, and job creation” said Diane Fabel, Director of Operations for the Center for Biotechnology. “Our academic institutions are incredible resources for bioscience companies to tap into when it comes to technology development, and promoting interactions between the two helps fuel the overall bioscience ecosystem in the region.”

The ARAD Program is part of a suite of programs and services provided by the Center for Biotechnology (CFB) focused on accelerating the development of biomedical technologies in order to have a positive impact on human health and society. The CFB is also the lead administrative institution for the Long Island Bioscience Hub (LIBH) an NIH-designated Research Evaluation and Commercialization Hub (REACH) established with a National Institutes of Health grant in 2015.

2017-2018 Applied Research and Development Awards 

“Synthetic Osteogenic Peptide for Treatment of Osteoporosis” Ajes Life Sciences & Dr. Srinivas Pentyala

“fMRI Dynamic Phantom for Improved Detection of Resting State Brain Networks” ALA Scientific Instruments & Dr. Helmut Strey

“Continued Development of ICU Temporary Pacemaker” Avery Biomedical Inc & Dr. Wei Lin

“Novel Pleiotropic Skin Brightening Agents” Biocogent, LLC & Dr. Sanford Simon

“In vivo Testing of Vaccine Candidates” Codagenix, Inc & Dr. Eckard Wimmer

“A Novel Polymeric Valve for Transcatheter Aortic Valve Replacement” Polynova Cardiovascular, Inc. & Dr. Danny Bluestein

“Imaging the Targeted Delivery of Biologic Agents to the Colon for Local Therapeutic Action” Symbiotic Health Inc. & Dr. Peter M. Smith-Jones

“Eradication of an Oncogenic Herpesvirus as a Novel Intervention for Lymphoma” Theragnostic Technologies, Inc. & Dr. Laurie T. Krug

“Novel Cancer Stem Cell Cytotoxic Agent: Nano-Formulation IND-Enabling Studies” TargaGenix Inc. & Dr. Galina Botchkina

Download a PDF of the press release here.

 

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                    [post_content] => 

Governor Kathy Hochul has unveiled plans for New York BioGenesis Park, a groundbreaking $430 million Cell and Gene Therapy (CGT) Innovation Hub in Nassau County, Long Island. To be developed by The Albanese Organization, Inc., this state-of-the-art facility would catalyze CGT research, development, clinical manufacturing, and commercialization across New York State. With a historic $150 million state investment—the largest nationwide for a cell and gene therapy hub—NYBGP would accelerate the delivery of new therapies from lab to patient in New York's diverse communities. This transformative hub aims to establish New York as the leading global destination for CGT innovation, driving economic growth, attracting top talent, and revolutionizing patient care statewide and beyond.

The Center for Biotechnology is thrilled to be counted as a partner in this effort, and is looking forward to working with our colleagues in the initiative to help catalyze and accelerate life-changing therapies.

New York BioGenesis Park is envisioned as a cutting-edge, full-service campus dedicated to advancing cell and gene therapies and accelerating their commercialization. At full build-out, the 700,000-square-foot park would create an end-to-end Cell and Gene Therapy innovation and supply center, featuring interconnected areas for public engagement, research, manufacturing, and collaboration.

A cornerstone of New York BioGenesis Park is its incubator, supported by a $50 million investment from ESD's Long Island Investment Fund. This facility will empower early-stage therapeutic developers by offering state-of-the-art wet lab space, shared equipment, office space, and other essential resources. This nurturing environment will provide Cell and Gene Therapy companies with access to specialized equipment, mentoring, and stage-appropriate financial guidance. As a critical component of New York BioGenesis Park, the incubator is poised to catalyze the growth of promising Cell and Gene Therapy companies by providing them with resources and support, unlocking their potential for innovation and success.

New York BioGenesis Park would foster strong ties with academic and medical institutions throughout New York, creating a robust ecosystem for Cell and Gene Therapy innovation. Collaborating with the Empire State Cellular Therapy Consortium and world-class institutions like Cold Spring Harbor Laboratory, the Feinstein Institutes, Northwell Health, Roswell Park, Stony Brook University, Weill Cornell, Columbia University and others around the state, New York BioGenesis Park would enhance research synergies and accelerate medical breakthroughs. This ecosystem would bring together experts in advanced Cell and Gene Therapy therapies, offering specialized facilities, services, and resources to both tenants and collaborating institutions. By facilitating cutting-edge science, innovative technology development and novel approaches to clinical trials, New York BioGenesis Park would ensure New York's institutions remain globally competitive in groundbreaking Cell and Gene Therapy research and commercialization.

Read the press release of Governor Hochul's announcement here:
https://www.governor.ny.gov/news/governor-hochul-launches-next-phase-long-islands-nation-leading-cell-and-gene-therapy

[post_title] => Long Island to be location for Nation-Leading Cell and Gene Therapy Innovation Hub: New York BioGenesis Park. [post_excerpt] => [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => long-island-to-be-location-for-nation-leading-cell-and-gene-therapy-innovation-hub-new-york-biogenesis-park [to_ping] => [pinged] => [post_modified] => 2025-02-26 16:35:20 [post_modified_gmt] => 2025-02-26 21:35:20 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=4488 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [1] => WP_Post Object ( [ID] => 4231 [post_author] => 4 [post_date] => 2023-07-10 12:37:00 [post_date_gmt] => 2023-07-10 16:37:00 [post_content] =>

SBU Startup, Lahara Bio, presented in the start-up stadium event at the 2023 BIO International Convention in June.

Christopher Ashdown, a MD/PhD student at Stony Brook University, and Center for Biotechnology Program alumnus presented on behalf of Lahara after securing a spot in the coveted forum by winning multiple pitch competitions from NIH SEED office.

According to Ashdown, “Bio 2023 was an amazing experience, and I was thrilled to be able to share the exciting work that we're doing at Lahara Bio with the greater bioscience community. The CfB was incredibly helpful in preparing the company for this conference and has done an excellent job of helping me develop on a personal/professional level".

In addition to the main stage presentation, Ashdown also presented Lahara Bio at the NIH booth. Lahara Bio was sponsored to attend BIO by the NIH after Ashdown won the national investor pitch competition at the NIH Proof of Concept Network annual meeting this past spring.

Lahara Bio is an early-stage biotechnology company using cell-specific mechanical vibration to non-invasively improve biomanufacturing outcomes. Learn more about the company and the team behind Lahara at laharabio.com.

[post_title] => Lahara Bio Presents at BIO International Convention [post_excerpt] => Stony Brook Start Up, Lahara Bio, was presented at the 2023 BIO International Convention by Christopher Ashdown, a MD/PhD student at Stony Brook University, and Center for Biotechnology Program alumnus. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => lahara-bio-presents-at-bio-international-convention [to_ping] => [pinged] => [post_modified] => 2024-08-22 11:32:58 [post_modified_gmt] => 2024-08-22 15:32:58 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=4231 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 3266 [post_author] => 3 [post_date] => 2019-05-21 18:27:06 [post_date_gmt] => 2019-05-21 18:27:06 [post_content] => Two important updates regarding upcoming BARDA DRIVe funding opportunities:  Drive Special Instructions – Due May 28! White papers, quad chart, and application form for the DRIVe special instructions to the BARDA BAA are due by 3:00 PM ET on Tuesday May 28th, 2019. Focus areas are: • 15.1: Advanced Research and Development of Sepsis Diagnostics and Devices • 15.2: Post-sepsis Monitoring • 16.1: On-Person, Wearable, and Biosensing Devices (Host Response and Direct Pathogen Detection) Steps to apply: 1.Review Solicitation BAA-18-100-SOL-00003 on fbo.gov. 2.Schedule a meeting with the ENACT or Solving Sepsis team (strongly encouraged). 3.Download the DRIVe Special Instructions Submission Form.* 4.Complete the PDF form, Quad Chart, White Paper, and Addendum (ROM cost estimate). 5. Email your submission to DRIVeContracting@hhs.gov by 3:00PM ET on May 28th. 6. You will receive an email notification confirming receipt within 5 business days. DRIVe personnel will review your white paper as described in the solicitation. 7. DRIVe personnel will notify you of the outcome of that review and may invite you to submit a full proposal. *You must download the PDF, as filling it out in a browser window will disable some key functionality. General DRIVe EZ-BAA - Deadline Extended  The deadline for DRIVe’s EZ-BAA has been extended to 3:00 PM ET on November 15th, 2019. Applications are reviewed on a rolling basis with a response as early as 30 days after submission. DRIVe has a new online portal for submitting EZ-BAA. Note: Companies must register for a profile in the online portal here, it can take up to 1 business day to account to be created. [post_title] => DRIVe Special Instructions & EZ-BAA Updates [post_excerpt] => DRIVe special instructions to the BARDA BAA are due by 3:00 PM ET on Tuesday May 28th! General application deadline for EZ-BAA extended until November 15th. [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => drive-special-instructions-ez-baa-updates [to_ping] => [pinged] => [post_modified] => 2019-05-21 18:27:06 [post_modified_gmt] => 2019-05-21 18:27:06 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=3266 [menu_order] => 95 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 3290 [post_author] => 3 [post_date] => 2019-07-18 19:14:24 [post_date_gmt] => 2019-07-18 19:14:24 [post_content] => Phase 0 Proof-of-Concept Partnership pilot program demonstrates effectiveness for transitioning basic science discoveries into the commercialization pipeline. The Long Island Bioscience Hub (LIBH), a National Institutes of Health (NIH) Research Evaluation and Commercialization Hub (REACH), is pleased to announce it has demonstrated significant impact as outlined in a recent evaluative report presenting the results and activities of the NIH REACH program over the pilot period of three years. The LIBH, a collaboration between Stony Brook University, Brookhaven National Laboratory, Cold Spring Harbor Laboratory, and the Feinstein Institute at Northwell Health, led by the Center for Biotechnology, was formed in March 2015 with a mission to help commercialize biomedical technologies emerging from the region’s research institutions. The report, prepared independently by RTI International on behalf of the NIH, outlines multiple outcomes from the REACH program, and documents the successes that the LIBH has had during the relatively short pilot phase of its work. The LIBH engaged 600 innovators in training sponsored or co-sponsored by the REACH Program. Fifty technology development projects have been funded by LIBH over the course of three years, including technologies focused on biologic drugs, diagnostic devices, small molecule drugs, therapeutic devices, and Health IT among others. As a result of the NIH investment in the LIBH, ten startup companies have been formed and two license agreements have been executed. In addition, the initial investment made by NIH in the region has generated follow on funding of more than $10 million, $2.8 million coming from five funded SBIR/STTR proposals based on LIBH technologies. This impact from the REACH program contributes to the overall economic impact of Center for Biotechnology, notably $1.2B over a recent fifteen year period. “We are thrilled with the outcomes reported in the RTI evaluation for the Long Island Bioscience Hub’s efforts thus far under the REACH program” said Clinton T. Rubin, Ph.D., Distinguished Professor, Department of Biomedical Engineering, and Director, Center for Biotechnology. “Through the REACH program we’ve been able to expand on the region’s efforts to commercialize more innovation locally, thereby capturing more of the economic impact within the region. While the pilot program will end in mid-2019, these impacts clearly demonstrate the potential of the model to make significant contributions to our innovation ecosystem.” “The RTI evaluation reinforces our knowledge that the Long Island Bioscience Hub model has already had a significant, positive impact on technologies and innovators embedded in our research community” stated Dr. Richard Reeder, Vice President for Research at Stony Brook University. “It is imperative we continue to fuel the activities of the LIBH as it is an essential part of innovation economy, and is a significant engine in bringing lifesaving technologies to patients.” The Center for Biotechnology, in collaboration with other partners in the region, will continue to explore how the model might be continued and expanded. Click here for PDF version. [post_title] => Long Island Bioscience Hub Reports Significant Impacts [post_excerpt] => The Long Island Bioscience Hub, is pleased to announce it has demonstrated significant impact as outlined in a recent evaluative report presenting the results and activities of the NIH REACH program over the pilot period of three years. 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Governor Kathy Hochul has unveiled plans for New York BioGenesis Park, a groundbreaking $430 million Cell and Gene Therapy (CGT) Innovation Hub in Nassau County, Long Island. To be developed by The Albanese Organization, Inc., this state-of-the-art facility would catalyze CGT research, development, clinical manufacturing, and commercialization across New York State. With a historic $150 million state investment—the largest nationwide for a cell and gene therapy hub—NYBGP would accelerate the delivery of new therapies from lab to patient in New York's diverse communities. This transformative hub aims to establish New York as the leading global destination for CGT innovation, driving economic growth, attracting top talent, and revolutionizing patient care statewide and beyond.

The Center for Biotechnology is thrilled to be counted as a partner in this effort, and is looking forward to working with our colleagues in the initiative to help catalyze and accelerate life-changing therapies.

New York BioGenesis Park is envisioned as a cutting-edge, full-service campus dedicated to advancing cell and gene therapies and accelerating their commercialization. At full build-out, the 700,000-square-foot park would create an end-to-end Cell and Gene Therapy innovation and supply center, featuring interconnected areas for public engagement, research, manufacturing, and collaboration.

A cornerstone of New York BioGenesis Park is its incubator, supported by a $50 million investment from ESD's Long Island Investment Fund. This facility will empower early-stage therapeutic developers by offering state-of-the-art wet lab space, shared equipment, office space, and other essential resources. This nurturing environment will provide Cell and Gene Therapy companies with access to specialized equipment, mentoring, and stage-appropriate financial guidance. As a critical component of New York BioGenesis Park, the incubator is poised to catalyze the growth of promising Cell and Gene Therapy companies by providing them with resources and support, unlocking their potential for innovation and success.

New York BioGenesis Park would foster strong ties with academic and medical institutions throughout New York, creating a robust ecosystem for Cell and Gene Therapy innovation. Collaborating with the Empire State Cellular Therapy Consortium and world-class institutions like Cold Spring Harbor Laboratory, the Feinstein Institutes, Northwell Health, Roswell Park, Stony Brook University, Weill Cornell, Columbia University and others around the state, New York BioGenesis Park would enhance research synergies and accelerate medical breakthroughs. This ecosystem would bring together experts in advanced Cell and Gene Therapy therapies, offering specialized facilities, services, and resources to both tenants and collaborating institutions. By facilitating cutting-edge science, innovative technology development and novel approaches to clinical trials, New York BioGenesis Park would ensure New York's institutions remain globally competitive in groundbreaking Cell and Gene Therapy research and commercialization.

Read the press release of Governor Hochul's announcement here:
https://www.governor.ny.gov/news/governor-hochul-launches-next-phase-long-islands-nation-leading-cell-and-gene-therapy

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Long Island to be location for Nation-Leading Cell and Gene Therapy Innovation Hub: New York BioGenesis Park.

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