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Anti-Cancer Agent Developed at SBU Shows Great Promise Against Tumors, Receives $24M Investment

A second-generation taxane conjugate in a nanoemulsion formulation (called NE-DHA-SBT-1214) developed by Stony Brook University Distinguished Professor Iwao Ojima in his chemistry laboratory and through the Institute of Chemical Biology & Drug Discovery (ICB&DD) and licensed to Dr. James Egan, has received a $24 million investment to be taken to phase 2a development. Preclinical results have persuaded TVM Capital Life Science to invest in the technology via Recurv Pharma.

The VC fund will invest up to $24 million in Recurv through its project-focused company (PFC) investment objective, an initiative focused on backing first or best-in-class candidates that are clearly differentiated from the competition or add clinical value. Read More on Fierce Pharma and via SBU News.

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CFB Client, IAMBIC has been awarded approximately $1M in grant funding from the National Science Foundation Small Business Innovation Research program. IAMBIC is an innovative shoe company disrupting the centuries-old footwear industry with their sizeless, precision-fit footwear driven by proprietary AI algorithms. This substantial funding from NSF enables IAMBIC to scale its cutting-edge precision-fit shoe design and manufacturing.

The Center for Biotechnology and its accelerator programs have been instrumental in assisting IAMBIC with their SBIR pursuits and commercialization development.

Read more about IAMBIC and their recent funding here.

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Established in April 2023, Stony Brook University's Center for Healthy Aging aims to promote healthy aging and extend physical and mental well-being through innovative research solutions. Please join them for our inaugural virtual seminar series.

Dr. Payel Sen, Stadtman Investigator, NIH
Epigenetic mechanisms of tissue aging
September 25th at 11 am
https://stonybrook.zoom.us/j/98037022918?pwd=XT2p35EKbehaazZpb0aLJtOW3a8gE1.1
Meeting ID: 980 3702 2918
Passcode: 426599

As we age, changes in our “epigenome” alter how our genes are regulated, ultimately impacting organ function. Our research focuses on understanding epigenomic changes in different organs. In this presentation, I will focus on skeletal muscle, which makes up 40% of our body weight and plays a key role in metabolism. As we age, our muscles tend to weaken, partly because the stem cells in our muscles that help repair and grow reduce in number and function. In our study, we looked at muscle stem cells from young, old, and geriatric mice and uncovered that as these cells age, they show signs of increased immune activity and start to lose their ability to stay dormant, which is vital for their function. We also identified specific areas of the genome that might be responsible for these changes. By targeting these areas, we could potentially restore the function of these stem cells and help maintain muscle health as we age.

Upcoming Topics & Dates:

  • October 30th, 11 am: Samantha Rossano, PhD, Medical Science Liaison, Life Molecular Imaging, Inc., Brain imaging biomarkers in Alzheimer’s disease
  • November 20th, 11 am: Gregorio Valdez, PhD, GLF Translational Associate Professor of Molecular Biology, Cell Biology and Biochemistry, Brown University, Slowing muscle degeneration
  • February 26th, 11 am: Christopher Barrett Bowling, MD, MSPH, Associate Professor of Medicine, Associate Professor in Population Health Sciences, Senior Fellow of the Center for the Study of Aging and Human Development, Duke University, Geriatricizing chronic disease research
  • March 26th, 11 am: Dr. Frank Lin, MD, PhD, Director of the Cochlear Center for Hearing and Public Health, Professor of Otolaryngology, Medicine, Mental Health, and Epidemiology, Johns Hopkins University Team, Baltimore HEARS and the Baltimore Longitudinal Study of Aging
  • April 30th, 11 am: Dennis Selkoe, MD, Vincent and Stella Coates Professor of Neurologic Diseases, Harvard University, Role of soluble oligomers of amyloid beta in synaptic injury

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The first virtual Health Security Innovation Showcase is being held on October 18 from 12 pm – 5 pm EDT to learn about high impact life science startups being supported by BARDA partners, including, CARB-X, the BARDA Accelerator Network, and the BARDA-J&J Blue Knight program. These companies are developing platform technologies in a variety of technology areas, including diagnostic tools, therapeutics/vaccines, advanced manufacturing, and clinical trial support.

Highlights of the event:

- A Keynote address by Dr. Gary Disbrow, Director of BARDA
- 5-minute pitches by each company, followed by 3 minutes of Q&A
- Overviews of BARDA programs supporting innovation in the health security space
- Opportunities for you to set up one-on-one partnering meetings with the presenting companies

The event platform will contain company profiles, pitch decks and live calendars to be used to facilitate and set up meetings. Once registered, additional details will be provided on how to access and view the details of the participating companies.

Click here to register*

*When your registration request is approved, you will receive an email from the event system asking you to log in and fill out your profile.

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CFB Client, IAMBIC has been awarded approximately $1M in grant funding from the National Science Foundation Small Business Innovation Research program. IAMBIC is an innovative shoe company disrupting the centuries-old footwear industry with their sizeless, precision-fit footwear driven by proprietary AI algorithms. This substantial funding from NSF enables IAMBIC to scale its cutting-edge precision-fit shoe design and manufacturing.

The Center for Biotechnology and its accelerator programs have been instrumental in assisting IAMBIC with their SBIR pursuits and commercialization development.

Read more about IAMBIC and their recent funding here.

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CFB Client IAMBIC Receives $1 Million NSF SBIR Phase II Grant

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SBU Center for Healthy Aging Seminar Series

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The Entrepreneur’s Toolkit Workshop – April 21, 2015

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Health Security Innovation Showcase – 10/18

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