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NHLBI Exploratory Research Grant for Bioengineers

A Notice of Special Interest (NOSI) has been issued by the National Heart, Lung, and Blood Institute (NHLBI) to encourage early-stage innovative bioengineering projects that could lead to preclinical and translational research and potential funding from federal and non-federal sources. The program is distinct from the NHLBI Catalyze Program and is focused on investigator-initiated ideas and concepts that may eventually contribute to the Catalyze pipeline.

This NOSI invites discovery- and design-driven bioengineering research ideas that are important across the Institute and critical for future hypothesis-generating projects. Notably, this program emphasizes first-generation prototype development and initial feasibility studies. The NHLBI is interested in the development of new ideas for diagnostics, therapeutics, surgical technologies, artificial intelligence/machine learning/computational modeling tools, smart biomaterials for self-adjusting implants, molecular imaging, synthetic biology, and nanotechnologies, as applied to HLBS-related issues.

First Available Due Date: February 16, 2025

Read the full NOSI and details on applying here: https://grants.nih.gov/grants/guide/notice-files/NOT-HL-24-037.html

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                    [post_content] => 

The Redesignation brings $10 million in funding to drive innovation, company formation, and economic growth.

The Center for Biotechnology (CFB) has announced its re-designated as a Center for Advanced Technology (CAT) by Empire State Development's Division of Science, Technology and Innovation (NYSTAR), a recognition that comes with $1 million in annual funding over the next ten years. The $10 million commitment underscores the CFB’s leadership in accelerating life science innovation, supporting early-stage technology development, and fueling economic growth through start-up formation and industry partnerships.

“The Center for Biotechnology has served as a critical bridge between academic research and commercial success,” said Dr. Clinton Rubin, Director of the Center for Biotechnology. “This re-designation ensures we can continue to expand our impact, helping innovators bring breakthrough technology to market and strengthening New York’s position as a leader in the bioscience industry.”

Empire State Development President, CEO and Commissioner Hope Knight said, “NYSTAR’s Centers for Advanced Technology are vital to our strategic efforts to grow New York’s economy and the state’s greater innovation ecosystem. By investing in the industries of tomorrow, New Yorkers benefit today through dynamic partnerships that help to create new jobs, generate more revenues, and encourage more companies to establish a footprint in communities all throughout the state.”

The Center for Biotechnology is located on the campus of Stony Brook University (SBU), the flagship research institution within the prestigious State University of New York (SUNY) system. Stony Brook University is recognized as a national and global leader in life sciences research, biomedical innovation, and clinical care. Situated on Long Island, New York, Stony Brook has built a formidable reputation as a hub for cutting-edge scientific discovery and translational medicine. The Center for Biotechnology builds upon these strengths by providing cutting-edge programming and competitive financial support to advance biomedical innovation and emerging company growth.

“We are excited to build upon the successful foundation of strong entrepreneurial networks, infrastructure, and programming that we have built over the last four decades” said Dr. Diane Fabel, Chief Operating Officer at the Center for Biotechnology. “The impacts we have had during our last designation period include over $1B in total economic impact with more than 1000 jobs created, and driving more than $315M in follow-on funding. We are excited to see those numbers continue to grow when we celebrate fifty years of hard work at the end of this redesignation period”.

As part of the New York State CAT program, the CFB will continue to work with emerging and established companies across the state to de-risk early-stage technologies, advance both technology and company value, foster public-private collaboration, and provide critical infrastructure for the region’s growing life science ecosystem. Additionally, the CFB team will continue its efforts to develop a life sciences workforce to support the region's bio-innovation economy with a specific emphasis on sectors deemed important to the NYS economy.

Dowload the full press release here.

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Governor Kathy Hochul has unveiled plans for New York BioGenesis Park, a groundbreaking $430 million Cell and Gene Therapy (CGT) Innovation Hub in Nassau County, Long Island. To be developed by The Albanese Organization, Inc., this state-of-the-art facility would catalyze CGT research, development, clinical manufacturing, and commercialization across New York State. With a historic $150 million state investment—the largest nationwide for a cell and gene therapy hub—NYBGP would accelerate the delivery of new therapies from lab to patient in New York's diverse communities. This transformative hub aims to establish New York as the leading global destination for CGT innovation, driving economic growth, attracting top talent, and revolutionizing patient care statewide and beyond.

The Center for Biotechnology is thrilled to be counted as a partner in this effort, and is looking forward to working with our colleagues in the initiative to help catalyze and accelerate life-changing therapies.

New York BioGenesis Park is envisioned as a cutting-edge, full-service campus dedicated to advancing cell and gene therapies and accelerating their commercialization. At full build-out, the 700,000-square-foot park would create an end-to-end Cell and Gene Therapy innovation and supply center, featuring interconnected areas for public engagement, research, manufacturing, and collaboration.

A cornerstone of New York BioGenesis Park is its incubator, supported by a $50 million investment from ESD's Long Island Investment Fund. This facility will empower early-stage therapeutic developers by offering state-of-the-art wet lab space, shared equipment, office space, and other essential resources. This nurturing environment will provide Cell and Gene Therapy companies with access to specialized equipment, mentoring, and stage-appropriate financial guidance. As a critical component of New York BioGenesis Park, the incubator is poised to catalyze the growth of promising Cell and Gene Therapy companies by providing them with resources and support, unlocking their potential for innovation and success.

New York BioGenesis Park would foster strong ties with academic and medical institutions throughout New York, creating a robust ecosystem for Cell and Gene Therapy innovation. Collaborating with the Empire State Cellular Therapy Consortium and world-class institutions like Cold Spring Harbor Laboratory, the Feinstein Institutes, Northwell Health, Roswell Park, Stony Brook University, Weill Cornell, Columbia University and others around the state, New York BioGenesis Park would enhance research synergies and accelerate medical breakthroughs. This ecosystem would bring together experts in advanced Cell and Gene Therapy therapies, offering specialized facilities, services, and resources to both tenants and collaborating institutions. By facilitating cutting-edge science, innovative technology development and novel approaches to clinical trials, New York BioGenesis Park would ensure New York's institutions remain globally competitive in groundbreaking Cell and Gene Therapy research and commercialization.

Read the press release of Governor Hochul's announcement here:
https://www.governor.ny.gov/news/governor-hochul-launches-next-phase-long-islands-nation-leading-cell-and-gene-therapy

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For a limited time, the Center for Biotechnology, as part of the NYS Designated Downstate SBIR/STTR Hub, is able to offer enhanced levels of support for SBIR/STTR proposal development and implementation. With support from Empire State Development, New York State companies are eligible to access services to help them learn about, develop, and execute SBIR/STTR proposals. Support during this limited time period includes:

- Access to short webinars and intensive workshops covering major federal agencies within the SBIR/STTR program
- One-on-one iterative proposal development consulting hours with SBIR experts
- Access to professional grant writing services
- Post award implementation consulting

Full details about the program can be found here: https://centerforbiotechnology.org/resources/programs/

Contact Kate Hutchinson (kate.hutchinson@stonybrook.edu) with questions.

[post_title] => Limited Time Enhanced SBIR/STTR Support [post_excerpt] => The Center for Biotechnology is offering enhanced SBIR/STTR proposal development assistance for a limited time. [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => limited-time-enhanced-sbir-sttr-support [to_ping] => [pinged] => [post_modified] => 2022-08-22 13:07:28 [post_modified_gmt] => 2022-08-22 13:07:28 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=3858 [menu_order] => 29 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 2364 [post_author] => 4 [post_date] => 2016-08-11 17:51:20 [post_date_gmt] => 2016-08-11 17:51:20 [post_content] => iCell Gene Therapeutics, a CFB client company, has announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation for its chimeric antigen receptor engineered T-cells directed against the target protein CD4 (CD4CAR) for the treatment of peripheral T-cell lymphoma (PTCL). The Orphan Drug Designation program provides orphan status, and associated development incentives, to drugs and biologics intended for the safe and effective treatment, diagnosis or prevention of rare diseases or disorders that affect fewer than 200,000 people in the U.S. Read more about the designation and company here. iCell [post_title] => iCell Gene Therapeutics Granted Orphan Drug Designation [post_excerpt] => iCell Gene Therapeutics, a CFB client company, has announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation for its chimeric antigen receptor engineered T-cells directed against the target protein CD4 (CD4CAR) for the treatment of peripheral T-cell lymphoma (PTCL). [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => icell-gene-therapeutics-granted-orphan-drug-designation [to_ping] => [pinged] => [post_modified] => 2017-01-09 15:08:30 [post_modified_gmt] => 2017-01-09 15:08:30 [post_content_filtered] => [post_parent] => 0 [guid] => http://centerforbiotechnology.org/?p=2364 [menu_order] => 168 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [4] => WP_Post Object ( [ID] => 3368 [post_author] => 3 [post_date] => 2019-09-23 14:41:34 [post_date_gmt] => 2019-09-23 14:41:34 [post_content] => As outlined by MarketWatch, a recent study shows that Stony Brook University as one of the top 10 U.S. colleges and universities that best promote upward mobility. The editorial further outlines many areas in which Stony Brook University is setting up its graduates for success noting that over the past five years, Stony Brook has improved graduation rates across the board. Read the full piece here. [post_title] => Stony Brook University Among Top Colleges for Upward Mobility [post_excerpt] => Stony Brook University "has a high-tech, data-driven focus on student performance and a high-touch, advisor-heavy outreach program to make sure kids stay on track." [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => stony-brook-university-among-top-colleges-for-upward-mobility [to_ping] => [pinged] => [post_modified] => 2019-09-23 20:09:46 [post_modified_gmt] => 2019-09-23 20:09:46 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=3368 [menu_order] => 84 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) ) [post_count] => 5 [current_post] => -1 [before_loop] => 1 [in_the_loop] => [post] => WP_Post Object ( [ID] => 4906 [post_author] => 4 [post_date] => 2025-07-17 10:27:09 [post_date_gmt] => 2025-07-17 14:27:09 [post_content] =>

The Redesignation brings $10 million in funding to drive innovation, company formation, and economic growth.

The Center for Biotechnology (CFB) has announced its re-designated as a Center for Advanced Technology (CAT) by Empire State Development's Division of Science, Technology and Innovation (NYSTAR), a recognition that comes with $1 million in annual funding over the next ten years. The $10 million commitment underscores the CFB’s leadership in accelerating life science innovation, supporting early-stage technology development, and fueling economic growth through start-up formation and industry partnerships.

“The Center for Biotechnology has served as a critical bridge between academic research and commercial success,” said Dr. Clinton Rubin, Director of the Center for Biotechnology. “This re-designation ensures we can continue to expand our impact, helping innovators bring breakthrough technology to market and strengthening New York’s position as a leader in the bioscience industry.”

Empire State Development President, CEO and Commissioner Hope Knight said, “NYSTAR’s Centers for Advanced Technology are vital to our strategic efforts to grow New York’s economy and the state’s greater innovation ecosystem. By investing in the industries of tomorrow, New Yorkers benefit today through dynamic partnerships that help to create new jobs, generate more revenues, and encourage more companies to establish a footprint in communities all throughout the state.”

The Center for Biotechnology is located on the campus of Stony Brook University (SBU), the flagship research institution within the prestigious State University of New York (SUNY) system. Stony Brook University is recognized as a national and global leader in life sciences research, biomedical innovation, and clinical care. Situated on Long Island, New York, Stony Brook has built a formidable reputation as a hub for cutting-edge scientific discovery and translational medicine. The Center for Biotechnology builds upon these strengths by providing cutting-edge programming and competitive financial support to advance biomedical innovation and emerging company growth.

“We are excited to build upon the successful foundation of strong entrepreneurial networks, infrastructure, and programming that we have built over the last four decades” said Dr. Diane Fabel, Chief Operating Officer at the Center for Biotechnology. “The impacts we have had during our last designation period include over $1B in total economic impact with more than 1000 jobs created, and driving more than $315M in follow-on funding. We are excited to see those numbers continue to grow when we celebrate fifty years of hard work at the end of this redesignation period”.

As part of the New York State CAT program, the CFB will continue to work with emerging and established companies across the state to de-risk early-stage technologies, advance both technology and company value, foster public-private collaboration, and provide critical infrastructure for the region’s growing life science ecosystem. Additionally, the CFB team will continue its efforts to develop a life sciences workforce to support the region's bio-innovation economy with a specific emphasis on sectors deemed important to the NYS economy.

Dowload the full press release here.

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Center for Biotechnology Announces Redesignation as New York State Center for Advanced Technology

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Long Island to be location for Nation-Leading Cell and Gene Therapy Innovation Hub: New York BioGenesis Park.

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Limited Time Enhanced SBIR/STTR Support

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iCell Gene Therapeutics Granted Orphan Drug Designation

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Stony Brook University Among Top Colleges for Upward Mobility

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