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Anti-Cancer Agent Developed at SBU Shows Great Promise Against Tumors, Receives $24M Investment

A second-generation taxane conjugate in a nanoemulsion formulation (called NE-DHA-SBT-1214) developed by Stony Brook University Distinguished Professor Iwao Ojima in his chemistry laboratory and through the Institute of Chemical Biology & Drug Discovery (ICB&DD) and licensed to Dr. James Egan, has received a $24 million investment to be taken to phase 2a development. Preclinical results have persuaded TVM Capital Life Science to invest in the technology via Recurv Pharma.

The VC fund will invest up to $24 million in Recurv through its project-focused company (PFC) investment objective, an initiative focused on backing first or best-in-class candidates that are clearly differentiated from the competition or add clinical value. Read More on Fierce Pharma and via SBU News.

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Applications are now open for the 12th BioREACH Award Program from the Center for Biotechnology, which provides $50,000 in translational research funding for Stony Brook faculty and postdoctoral researchers to generate the evidence needed to advance promising innovations to the next stage of development.

BioREACH funds milestone-driven studies and welcomes biomedical innovations as well as platforms, tools, computational technologies, and other enabling technologies with the potential to contribute to solutions addressing unmet needs in health.

Application deadline: October 29, 2026, 5:00pm ET

For info sessions, eligibility and deadlines visit our REACH Website and FAQ.

The Center for Biotechnology (CfB) has helped advance some of Stony Brook University’s most impactful biomedical innovations, among them the yeast two-hybrid system, Xiaflex®, ReoPro®, Oracea®, and 3D virtual colonoscopy. The CfB has supported more than 475 faculty-led translational research projects and contributed to 306 license agreements generating $51 million in royalty returns to the University.

Questions? Reach out to our program contacts or sign up for office hours:

Dee Dao, PhD, Associate Director, dee.dao@stonybrook.edu
Office Hours: Monday–Friday, 2–3:30 PM | Sign up Here

Zelda Mendelowitz, PhD, Venture Associate, zelda.mendelowitz@stonybrook.edu
Office Hours: Tuesday, Wednesday, Friday, 8–11 AM | Sign up Here

[post_title] => BioREACH: Translational Research Funding Opportunity [post_excerpt] => [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => bioreach-translational-research-funding-opportunity [to_ping] => [pinged] => [post_modified] => 2026-09-04 11:55:36 [post_modified_gmt] => 2026-09-04 15:55:36 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=5065 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [1] => WP_Post Object ( [ID] => 3783 [post_author] => 3 [post_date] => 2021-05-26 16:31:40 [post_date_gmt] => 2021-05-26 16:31:40 [post_content] =>

Led by experts from BBC Entrepreneurial Training & Consulting, join our live Virtual Classroom for an interactive, 2 day SBIR/STTR workshop. We’ll review the basics including program purpose; eligibility; and sources of funding. Then we’ll provide proposal prep essentials of the NIH, NSF and DOE programs. In addition to up-to-date information on the SBIR/STTR programs, we will cover:

- NIH and NSF grant mechanisms and where to find them

- How to find the program officers, how to approach them, what questions to ask

- How to do research using the web tools available (eReporter, SBIR.gov, etc.)

- Common pitfalls and how to avoid them, and much more.

Workshop registration fee: $25.00. Please register online: https://cfbsbirtrain2021a.eventbrite.com. 

*Stony Brook University Faculty/Staff/Students may attend workshop at no cost – please contact Kate Hutchinson (kate.hutchinson@stonybrook.edu)  for details. 

Workshop is produced by the Center for Biotechnology at Stony Brook University and in partnership with Columbia Technology Ventures. The Center for Biotechnology also offers a follow on One-on-One Proposal Counseling program via a competitive application process. Learn more here: https://centerforbiotechnology.org/resources/programs/ 

[post_title] => Virtual SBIR/STTR Intensive Workshop - June 15 &16, 2021 [post_excerpt] => The Center for Biotechnology & Columbia Tech Ventures present a 2-day intensive SBIR/STTR workshop. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => virtual-sbir-sttr-intensive-workshop-june-15-16-2021 [to_ping] => [pinged] => https://centerforbiotechnology.org/resources/programs/ [post_modified] => 2021-09-20 16:05:00 [post_modified_gmt] => 2021-09-20 16:05:00 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=3783 [menu_order] => 45 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 4477 [post_author] => 4 [post_date] => 2024-09-10 13:59:15 [post_date_gmt] => 2024-09-10 17:59:15 [post_content] =>

Established in April 2023, Stony Brook University's Center for Healthy Aging aims to promote healthy aging and extend physical and mental well-being through innovative research solutions. Please join them for our inaugural virtual seminar series.

Dr. Payel Sen, Stadtman Investigator, NIH
Epigenetic mechanisms of tissue aging
September 25th at 11 am
https://stonybrook.zoom.us/j/98037022918?pwd=XT2p35EKbehaazZpb0aLJtOW3a8gE1.1
Meeting ID: 980 3702 2918
Passcode: 426599

As we age, changes in our “epigenome” alter how our genes are regulated, ultimately impacting organ function. Our research focuses on understanding epigenomic changes in different organs. In this presentation, I will focus on skeletal muscle, which makes up 40% of our body weight and plays a key role in metabolism. As we age, our muscles tend to weaken, partly because the stem cells in our muscles that help repair and grow reduce in number and function. In our study, we looked at muscle stem cells from young, old, and geriatric mice and uncovered that as these cells age, they show signs of increased immune activity and start to lose their ability to stay dormant, which is vital for their function. We also identified specific areas of the genome that might be responsible for these changes. By targeting these areas, we could potentially restore the function of these stem cells and help maintain muscle health as we age.

Upcoming Topics & Dates:

  • October 30th, 11 am: Samantha Rossano, PhD, Medical Science Liaison, Life Molecular Imaging, Inc., Brain imaging biomarkers in Alzheimer’s disease
  • November 20th, 11 am: Gregorio Valdez, PhD, GLF Translational Associate Professor of Molecular Biology, Cell Biology and Biochemistry, Brown University, Slowing muscle degeneration
  • February 26th, 11 am: Christopher Barrett Bowling, MD, MSPH, Associate Professor of Medicine, Associate Professor in Population Health Sciences, Senior Fellow of the Center for the Study of Aging and Human Development, Duke University, Geriatricizing chronic disease research
  • March 26th, 11 am: Dr. Frank Lin, MD, PhD, Director of the Cochlear Center for Hearing and Public Health, Professor of Otolaryngology, Medicine, Mental Health, and Epidemiology, Johns Hopkins University Team, Baltimore HEARS and the Baltimore Longitudinal Study of Aging
  • April 30th, 11 am: Dennis Selkoe, MD, Vincent and Stella Coates Professor of Neurologic Diseases, Harvard University, Role of soluble oligomers of amyloid beta in synaptic injury

[post_title] => SBU Center for Healthy Aging Seminar Series [post_excerpt] => Join Stony Brook's Center for Healthy Aging for their inaugural virtual seminar series. [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => https-centerforbiotechnology-org-sbu-cha-seminar-series [to_ping] => [pinged] => [post_modified] => 2024-12-05 11:36:33 [post_modified_gmt] => 2024-12-05 16:36:33 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=4477 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 2824 [post_author] => 4 [post_date] => 2017-09-20 13:41:33 [post_date_gmt] => 2017-09-20 13:41:33 [post_content] => Avanti Biosciences, Inc. a preclinical-stage biopharmaceutical company lead by Center for Biotechnology BioEntrepreneur-in-Residence Dr. Gian Luca Araldi, has announced that the National Institute of Aging (NIA) has awarded the Company an SBIR fast-track grant of up to $1,930,000 to support the company’s small molecule treatment for Alzheimer’s disease (AD) over the next 3 years. The award will enable the preparation and testing of Avanti’s proprietary compounds derivatized from natural catechins, which inhibit DYRK1A, an enzyme that modulates tau phosphorylation. Working with NY Institute for Basic Research and the University of California San Diego (UCSD), the company hopes to attenuate and potentially reverse pathogenesis for Alzheimer’s disease and other neurodegenerative diseases. “This award marks a significant milestone for Avanti Biosciences and an important step for their research into a treatment for Alzheimer’s disease” stated Dr. Clinton Rubin, Director of the New York State Center for Biotechnology at Stony Brook University. “The Center for Biotechnology is thrilled to see another success for one of the emerging bioscience companies fueling our regional bioecosystem and we proudly support Dr. Araldi’s work as one of our BioEntrepreneurs-in-Residence.” Dr. Gian Luca Araldi, Founder and Chief Executive Officer of Avanti, stated, “We are delighted to have been granted this funding from the NIA as it underscores the great need for innovative, effective treatments for this disease, and recognizes the potential benefits that our compounds may provide for patients with AD. The continuous support of Center for Biotechnology and the BioEntrepreneur-in-Residence program has been critical force in the development of our technology and the company as whole.” More than five million people in the United States are living with Alzheimer’s disease, a progressive, irreversible, neurodegenerative disease that destroys memory and other cognitive abilities. It is the sixth leading cause of death in the United States and as the aging population in the country grows, the incidence rate is expected to rise dramatically. Learn more about Avanti Biosciences: avantibiosciences.com [post_title] => CFB BEIR Receives $1.9M SBIR Fast-Track [post_excerpt] => Avanti Biosciences, Inc. a preclinical-stage biopharmaceutical company lead by CFB BioEntrepreneur-in-Residence Dr. Gian Luca Araldi, has announced that the National Institute of Aging (NIA) has awarded the Company an SBIR fast-track grant of up to $1,930,000 to support the company’s small molecule Alzheimer’s disease (AD) over the next 3 years. [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => cfb-beir-receives-1-9m-sbir-fast-track [to_ping] => [pinged] => [post_modified] => 2018-01-23 14:39:07 [post_modified_gmt] => 2018-01-23 14:39:07 [post_content_filtered] => [post_parent] => 0 [guid] => http://centerforbiotechnology.org/?p=2824 [menu_order] => 138 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) ) [post_count] => 4 [current_post] => -1 [before_loop] => 1 [in_the_loop] => [post] => WP_Post Object ( [ID] => 5065 [post_author] => 4 [post_date] => 2026-09-01 14:03:32 [post_date_gmt] => 2026-09-01 18:03:32 [post_content] =>

Applications are now open for the 12th BioREACH Award Program from the Center for Biotechnology, which provides $50,000 in translational research funding for Stony Brook faculty and postdoctoral researchers to generate the evidence needed to advance promising innovations to the next stage of development.

BioREACH funds milestone-driven studies and welcomes biomedical innovations as well as platforms, tools, computational technologies, and other enabling technologies with the potential to contribute to solutions addressing unmet needs in health.

Application deadline: October 29, 2026, 5:00pm ET

For info sessions, eligibility and deadlines visit our REACH Website and FAQ.

The Center for Biotechnology (CfB) has helped advance some of Stony Brook University’s most impactful biomedical innovations, among them the yeast two-hybrid system, Xiaflex®, ReoPro®, Oracea®, and 3D virtual colonoscopy. The CfB has supported more than 475 faculty-led translational research projects and contributed to 306 license agreements generating $51 million in royalty returns to the University.

Questions? Reach out to our program contacts or sign up for office hours:

Dee Dao, PhD, Associate Director, dee.dao@stonybrook.edu
Office Hours: Monday–Friday, 2–3:30 PM | Sign up Here

Zelda Mendelowitz, PhD, Venture Associate, zelda.mendelowitz@stonybrook.edu
Office Hours: Tuesday, Wednesday, Friday, 8–11 AM | Sign up Here

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BioREACH: Translational Research Funding Opportunity

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Virtual SBIR/STTR Intensive Workshop – June 15 &16, 2021

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SBU Center for Healthy Aging Seminar Series

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CFB BEIR Receives $1.9M SBIR Fast-Track

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