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Funding Opportunity – NHLBI Catalyze Program

The National Heart, Lung, and Blood Institute (NHLBI) Catalyze Program is soliciting applications for early stage translational research projects with the goal of developing basic scientific discoveries into viable therapeutics, devices, and diagnostics to treat heart, lung, blood, and sleep diseases and disorders.

Funding is available for early stage technology development, including:

Therapeutics (Small molecules/Biologics)
– Identifying and characterizing lead compounds

Devices/Diagnostics/Tools
– Developing, testing, and modifying prototypes
– Identifying and developing assay targets
– Developing research tools

Enabling Technologies and Transformative Platforms
– Developing highly-innovative, next-generation technologies that could transform current approaches to clinical practice or translational research (technology must be beyond proof-of-concept and should be ready to begin validation)
– Accelerating the areas of early detection and screening, animal model development, or clinical diagnosis

Learn more about the program and the informational webinar taking place on October 3, 2019 on the NHLBI website.

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CFB Client, IAMBIC has been awarded approximately $1M in grant funding from the National Science Foundation Small Business Innovation Research program. IAMBIC is an innovative shoe company disrupting the centuries-old footwear industry with their sizeless, precision-fit footwear driven by proprietary AI algorithms. This substantial funding from NSF enables IAMBIC to scale its cutting-edge precision-fit shoe design and manufacturing.

The Center for Biotechnology and its accelerator programs have been instrumental in assisting IAMBIC with their SBIR pursuits and commercialization development.

Read more about IAMBIC and their recent funding here.

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DepYmed, a joint venture of Cold Spring Harbor Laboratory and New York City-based biotech Ohr Pharmaceutical led by Andreas Grill, has received $100,000 from Accelerate Long Island and the Long Island Emerging Technologies Fund. Andreas Grill has served as a BioEntrepreneur-in-Residence for the center for Biotechnology and DepYmed is developing a new drug called Trodusquemine that it hopes will one day treat HER2-positive breast cancer, an aggressive form of the disease. Read more about the company and the investment from Accelerate and LIETF here.

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Stony Brook University, iCell Gene Therapeutics, and the University of Louisville, have received Food and Drug Administration (FDA) clearance for an Investigational New Drug (IND) for the treatment of relapsed and refractory T-cell leukemia and lymphoma. The approach is the first to use chimeric antigen receptor engineered T-cells directed against the target protein CD4 (CD4CAR). Together, Stony Brook University, the University of Louisville, and iCell Gene Therapeutics expect the first in-human Phase I clinical trial to begin accruing patients before the end of 2018. “We are excited to partner with the University of Louisville and iCell Gene Therapeutics to offer this innovative first-in-human CAR T cell immunotherapy clinical trial for patients who are suffering from these extremely difficult to treat T cell lymphomas and leukemias,” said Huda Salman, MD, Principal Investigator for the IND and an oncologist at Stony Brook University Cancer Center. “CD4CAR T cells may prove to be a promising and novel therapy in this setting.” “The development of this trial using CD4 as a target is the first of what we expect to be many CAR T-based clinical trials available to our patients over time,” said Yusuf Hannun, MD, Director of the Stony Brook University Cancer Center. “The pending trial is an example of the type of bench-to-bedside research that is building up at Stony Brook due to the growing expertise and collaborative research environment we are creating and new opportunities that will emerge upon the opening of our Medical and Research Translation (MART) Building.” William Tse, MD, FACP, Chief of the Blood and Marrow Transplantation at the University of Louisville School of Medicine, is the Co-PI of the CD4CAR clinical trial at University of Louisville site. [post_title] => Client News: First In-Human Clinical Trial Targeting CD4 Protein for Aggressive T-cell Leukemia and Lymphoma to be Launched [post_excerpt] => CFB Client iCell Gene Therapeutics, Stony Brook University, and the University of Louisville, have received FDA clearance for an Investigational New Drug (IND) for the treatment of relapsed and refractory T-cell leukemia and lymphoma. [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => client-news-first-in-human-clinical-trial-targeting-cd4-protein-for-aggressive-t-cell-leukemia-and-lymphoma-to-be-launched [to_ping] => [pinged] => [post_modified] => 2018-08-13 15:51:02 [post_modified_gmt] => 2018-08-13 15:51:02 [post_content_filtered] => [post_parent] => 0 [guid] => http://centerforbiotechnology.org/?p=3022 [menu_order] => 115 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 3305 [post_author] => 3 [post_date] => 2019-07-22 13:47:17 [post_date_gmt] => 2019-07-22 13:47:17 [post_content] => Stony Brook University faculty researchers and graduate students involved in research may sign up for a free, 1-day workshop from 8:30-5 on either Aug. 12 or Aug. 15 with the Alan Alda Center for Communicating Science. Workshops are highly interactive and participants must stay the full day. Alda Center workshops empower researchers to communicate their work clearly and vividly to all audiences. The Alda Center has worked with leading researchers from Yale, NASA, and U.S. Fish & Wildlife Service, and many others. SBU reserachers may register via this link: https://forms.gle/fvh3wNLYyQBoeXyi [post_title] => Alda Center Workshop for SBU Researchers [post_excerpt] => Stony Brook University faculty researchers and graduate students involved in research may sign up for a free, 1-day workshop with the Alan Alda Center for Communicating Science. 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CFB Client, IAMBIC has been awarded approximately $1M in grant funding from the National Science Foundation Small Business Innovation Research program. IAMBIC is an innovative shoe company disrupting the centuries-old footwear industry with their sizeless, precision-fit footwear driven by proprietary AI algorithms. This substantial funding from NSF enables IAMBIC to scale its cutting-edge precision-fit shoe design and manufacturing.

The Center for Biotechnology and its accelerator programs have been instrumental in assisting IAMBIC with their SBIR pursuits and commercialization development.

Read more about IAMBIC and their recent funding here.

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CFB Client IAMBIC Receives $1 Million NSF SBIR Phase II Grant

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Depymed Received $100k from Accelerate Long Island & LIETF

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Client News: First In-Human Clinical Trial Targeting CD4 Protein for Aggressive T-cell Leukemia and Lymphoma to be Launched

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Alda Center Workshop for SBU Researchers

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