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CFB Client, IAMBIC has been awarded approximately $1M in grant funding from the National Science Foundation Small Business Innovation Research program. IAMBIC is an innovative shoe company disrupting the centuries-old footwear industry with their sizeless, precision-fit footwear driven by proprietary AI algorithms. This substantial funding from NSF enables IAMBIC to scale its cutting-edge precision-fit shoe design and manufacturing.
The Center for Biotechnology and its accelerator programs have been instrumental in assisting IAMBIC with their SBIR pursuits and commercialization development.
Read more about IAMBIC and their recent funding here.
[post_title] => CFB Client IAMBIC Receives $1 Million NSF SBIR Phase II Grant
[post_excerpt] => This substantial funding from NSF enables IAMBIC to scale its operations.
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[post_content] => Avanti Biosciences, Inc. a preclinical-stage biopharmaceutical company lead by Center for Biotechnology BioEntrepreneur-in-Residence Dr. Gian Luca Araldi, has announced that the National Institute of Aging (NIA) has awarded the Company an SBIR fast-track grant of up to $1,930,000 to support the company’s small molecule treatment for Alzheimer’s disease (AD) over the next 3 years.
The award will enable the preparation and testing of Avanti’s proprietary compounds derivatized from natural catechins, which inhibit DYRK1A, an enzyme that modulates tau phosphorylation. Working with NY Institute for Basic Research and the University of California San Diego (UCSD), the company hopes to attenuate and potentially reverse pathogenesis for Alzheimer’s disease and other neurodegenerative diseases.
“This award marks a significant milestone for Avanti Biosciences and an important step for their research into a treatment for Alzheimer’s disease” stated Dr. Clinton Rubin, Director of the New York State Center for Biotechnology at Stony Brook University. “The Center for Biotechnology is thrilled to see another success for one of the emerging bioscience companies fueling our regional bioecosystem and we proudly support Dr. Araldi’s work as one of our BioEntrepreneurs-in-Residence.”
Dr. Gian Luca Araldi, Founder and Chief Executive Officer of Avanti, stated, “We are delighted to have been granted this funding from the NIA as it underscores the great need for innovative, effective treatments for this disease, and recognizes the potential benefits that our compounds may provide for patients with AD. The continuous support of Center for Biotechnology and the BioEntrepreneur-in-Residence program has been critical force in the development of our technology and the company as whole.”
More than five million people in the United States are living with Alzheimer’s disease, a progressive, irreversible, neurodegenerative disease that destroys memory and other cognitive abilities. It is the sixth leading cause of death in the United States and as the aging population in the country grows, the incidence rate is expected to rise dramatically.
Learn more about Avanti Biosciences: avantibiosciences.com
[post_title] => CFB BEIR Receives $1.9M SBIR Fast-Track
[post_excerpt] => Avanti Biosciences, Inc. a preclinical-stage biopharmaceutical company lead by CFB BioEntrepreneur-in-Residence Dr. Gian Luca Araldi, has announced that the National Institute of Aging (NIA) has awarded the Company an SBIR fast-track grant of up to $1,930,000 to support the company’s small molecule Alzheimer’s disease (AD) over the next 3 years.
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[post_content] => iCell Gene Therapeutics, a CFB client company, has announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation for its chimeric antigen receptor engineered T-cells directed against the target protein CD4 (CD4CAR) for the treatment of peripheral T-cell lymphoma (PTCL). The Orphan Drug Designation program provides orphan status, and associated development incentives, to drugs and biologics intended for the safe and effective treatment, diagnosis or prevention of rare diseases or disorders that affect fewer than 200,000 people in the U.S. Read more about the designation and company here.
[post_title] => iCell Gene Therapeutics Granted Orphan Drug Designation
[post_excerpt] => iCell Gene Therapeutics, a CFB client company, has announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation for its chimeric antigen receptor engineered T-cells directed against the target protein CD4 (CD4CAR) for the treatment of peripheral T-cell lymphoma (PTCL).
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[post_content] => Stony Brook University Happenings recently profiled the Center for Biotechnology's designation as on of eight national accelerators under the Department of Health and Human Services’ (HHS) Biomedical Advanced Research and Development Authority (BARDA) Division of Research, Innovation and Ventures (DRIVe). Excerpt below, read the full article here.
Sepsis occurs when chemicals released into the bloodstream to fight an infection trigger inflammatory responses throughout the body. It’s dangerous and often deadly. According to the U.S. Department of Health and Human Services, more than 250,000 people die from sepsis each year, and it is a leading cause of hospitalization in the U.S.
What if a simple test could identify the onset of sepsis as soon as it occurs? Better yet, what if wearable technology was available to alert doctors about sepsis in a patient before they ever show symptoms?
This may be possible in the future thanks to Stony Brook University’s participation in the federal government’s new BARDA-DRIVe initiative.
[caption id="attachment_3007" align="alignleft" width="300"]
Stony Brook, NY; Stony Brook University: Center for Biotechnology's (CFB) Director of Operations Diane Fabel talks with Alyssa Tuthill, Instructional Support Associate/Biomedical Engineering Labs Manager while Graduate Research Assistant Vaughn Greene works with samples.[/caption]
The initiative, launched by the Division of Research, Innovation and Ventures (DRIVe), will be overseen by the Department of Health and Human Services’ (HHS) Biomedical Advanced Research and Development Authority (BARDA).
BARDA has selected Stony Brook’s Center for Biotechnology as one of eight national accelerators across the country to assist in scouting faculty innovators and businesses that are developing health security technology that meets the program’s goals. The initiative plans to focus first on sepsis and the early detection and diagnosis of infections that threaten national health. More goals will be identified over time.
“National health security is essential for optimum public health, enabling our society to thrive,” said Stony Brook University President Samuel L. Stanley Jr. President Stanley is a biomedical researcher who specializes in emerging infectious diseases. He also chairs the Innovation Committee for the Long Island Regional Economic Development Council.
“With a proven record of research, discovery, innovation and product-development in the biomedical sciences, Stony Brook’s Center for Biotechnology is poised to become an important contributor to the BARDA-DRIVe initiative,” he said. “I am certain that the Center will advance and accelerate research discovery, and strategically collaborate with biotech companies to find solutions to better manage sepsis and emerging national health issues.”
[post_title] => Center for Biotechnology Tapped for New Healthcare Security Innovation Program
[post_excerpt] => “With a proven record of research, discovery, innovation and product-development in the biomedical sciences, Stony Brook’s Center for Biotechnology is poised to become an important contributor to the BARDA-DRIVe initiative”
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CFB Client, IAMBIC has been awarded approximately $1M in grant funding from the National Science Foundation Small Business Innovation Research program. IAMBIC is an innovative shoe company disrupting the centuries-old footwear industry with their sizeless, precision-fit footwear driven by proprietary AI algorithms. This substantial funding from NSF enables IAMBIC to scale its cutting-edge precision-fit shoe design and manufacturing.
The Center for Biotechnology and its accelerator programs have been instrumental in assisting IAMBIC with their SBIR pursuits and commercialization development.
Read more about IAMBIC and their recent funding here.
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