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CFB BEIR Receives $1.9M SBIR Fast-Track

Avanti Biosciences, Inc. a preclinical-stage biopharmaceutical company lead by Center for Biotechnology BioEntrepreneur-in-Residence Dr. Gian Luca Araldi, has announced that the National Institute of Aging (NIA) has awarded the Company an SBIR fast-track grant of up to $1,930,000 to support the company’s small molecule treatment for Alzheimer’s disease (AD) over the next 3 years.

The award will enable the preparation and testing of Avanti’s proprietary compounds derivatized from natural catechins, which inhibit DYRK1A, an enzyme that modulates tau phosphorylation. Working with NY Institute for Basic Research and the University of California San Diego (UCSD), the company hopes to attenuate and potentially reverse pathogenesis for Alzheimer’s disease and other neurodegenerative diseases.

“This award marks a significant milestone for Avanti Biosciences and an important step for their research into a treatment for Alzheimer’s disease” stated Dr. Clinton Rubin, Director of the New York State Center for Biotechnology at Stony Brook University. “The Center for Biotechnology is thrilled to see another success for one of the emerging bioscience companies fueling our regional bioecosystem and we proudly support Dr. Araldi’s work as one of our BioEntrepreneurs-in-Residence.”

Dr. Gian Luca Araldi, Founder and Chief Executive Officer of Avanti, stated, “We are delighted to have been granted this funding from the NIA as it underscores the great need for innovative, effective treatments for this disease, and recognizes the potential benefits that our compounds may provide for patients with AD. The continuous support of Center for Biotechnology and the BioEntrepreneur-in-Residence program has been critical force in the development of our technology and the company as whole.”

More than five million people in the United States are living with Alzheimer’s disease, a progressive, irreversible, neurodegenerative disease that destroys memory and other cognitive abilities. It is the sixth leading cause of death in the United States and as the aging population in the country grows, the incidence rate is expected to rise dramatically.

Learn more about Avanti Biosciences: avantibiosciences.com

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CFB Client, IAMBIC has been awarded approximately $1M in grant funding from the National Science Foundation Small Business Innovation Research program. IAMBIC is an innovative shoe company disrupting the centuries-old footwear industry with their sizeless, precision-fit footwear driven by proprietary AI algorithms. This substantial funding from NSF enables IAMBIC to scale its cutting-edge precision-fit shoe design and manufacturing.

The Center for Biotechnology and its accelerator programs have been instrumental in assisting IAMBIC with their SBIR pursuits and commercialization development.

Read more about IAMBIC and their recent funding here.

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A Steering Committee formed of public health experts selects an annual Challenge topic. Entrepreneurs who participate in the Challenge will receive mentorship, participate in a bootcamp and will showcase their innovations and pitch at an annual Regional Symposium. Program notes: - Applications are due by 11:55PM EST on March 15, 2019 at www.nyhealthchallenge.com - The Healthcare Challenge is part of the U.S. Economic Development Administration’s Regional Innovation Strategies i6 Challenge and is hosted by Hofstra University’s Center for Entrepreneurship. - The signature prize money sponsor is Northwell Health, New York State’s largest healthcare provider and private employer. - The innovation must address the 2019 topic “Creating Wellness” and solve a healthcare problem facing one or more underserved communities in NYC, Long Island, and the Hudson Valley. - Entrepreneurs will participate in a Bootcamp, receive mentorship from healthcare experts, and have an opportunity to present at a Regional Symposium and Pitch Competition. - This year’s competition includes a $5,000 “Community Impact Award” for diverse entrepreneurs who are solving suburban healthcare issues sponsored by the Hofstra University National Center for Suburban Studies. - Prize money sponsors include Digital Remedy, Ernst & Young, Nixon Peabody, and the NuHealth Foundation. -  In-kind sponsors include Intelligent Product Solutions and the Hofstra ideaHUb. 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This year's event will take place on October 24-25 at 10 on the Park at the Time Warner Center in New York City. The objective of the meeting is to connect emerging companies with early-stage investors, business development professionals, and medical research foundations with the goal of advancing new innovations through clinical development. The robust, two-day program features: - Emerging Company Showcase - Pitch Doctor Sessions - Pipeline Café - Business Workshops & Plenary Sessions - Therapeutic Focused Panels - Online & Onsite Partnering - Strategic partners presentations View the full 2018 program and register at lifesciencessummit.org. [post_title] => Life Sciences Summit 2018: 10/24-10/25 [post_excerpt] => The Center for Biotechnology's annual Life Sciences Summit will take place on October 24-25 in New York City. 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Apply for the first cohort of FY2023 by Nov. 16!

The I-Corps™ at NIH Program helps current Phase I SBIR/STTR awardees from the NIH and CDC transition from researcher to entrepreneur.

This 8.5-week training program provides practical guidance from experienced industry professionals that will move you forward on your path toward commercialization. Past participants have written strong SBIR/STTR Phase II applications, won partnerships and investments, and built vast networks in the field.

Apply for the first cohort of FY2023 through the NIH ASSIST platform by 5:00 p.m. your local time on Wednesday, November 16.

Questions? Review the FAQs or contact us if you need help at icorps@mail.nih.gov.

Learn More and Apply: https://sbir.cancer.gov/commercialization/business/icorps

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CFB Client, IAMBIC has been awarded approximately $1M in grant funding from the National Science Foundation Small Business Innovation Research program. IAMBIC is an innovative shoe company disrupting the centuries-old footwear industry with their sizeless, precision-fit footwear driven by proprietary AI algorithms. This substantial funding from NSF enables IAMBIC to scale its cutting-edge precision-fit shoe design and manufacturing.

The Center for Biotechnology and its accelerator programs have been instrumental in assisting IAMBIC with their SBIR pursuits and commercialization development.

Read more about IAMBIC and their recent funding here.

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