Back to News & Events

Codagenix Inks Exclusive License Agreement

Codagenix, Inc. has entered into an exclusive licensing agreement with Stony Brook University, through the Research Foundation for the State of New York, to commercialize a platform technology to develop a pipeline of live attenuated vaccines against viral infections in people and animals. The technology relies on software to re-design the genomes of potentially harmful viruses to make them safe and effective vaccines. The technology stems from research in the laboratory of Eckard Wimmer, PhD, Distinguished Professor in the Department of Molecular Genetics & Microbiology. The lead indication for vaccine development generated is a vaccine against Seasonal Influenza slated for Phase I human clinical trials in 2017.

Dr. Wimmer, along with Steffen Mueller, PhD, Codagenix President and Chief Science Officer, and J. Robert Coleman, PhD, Codagenix Chief Operating officer, worked as colleagues for years in Dr. Wimmer’s laboratory examining and experimenting with the genes of viruses. By collaborating with Stony Brook scientists Bruce Futcher, PhD, in the Department of Molecular Genetics & Microbiology, and Steven Skienna, PhD, in the Department of Computer Science, they discovered a way using gene manipulation and computer algorithms to “re-code” the genes of viruses. This re-coding process makes viruses extremely weak and thus ideal candidates as ultra-low dose attenuated vaccines.

The licensing agreement enables Codgenix to develop and potentially market next generation vaccines using software-based gene design and whole viral synthesis to create low-dose, attenuated virus vaccines. The company expects to use this design to first test its vaccine against influenza; however, there are plans for human testing of their Zika and other vaccine candidates. Codagenix is also in partnership with a large agricultural company to make vaccines using the technology for companion and agricultural animals.

The technology has been shown to be effective against numerous viruses including ZIka, Dengue, and RSV all of which are in preclinical testing. The development of this pipeline of vaccines can be seen in numerous scientific papers since 2008, including a paper in Science, PNAS, National Biotechnology and most recently in 2015 in MBIo.

Read Stony Brook University’s full press release here. 

Related Stories

WP_Query Object
(
    [query] => Array
        (
            [post_type] => post
            [posts_per_page] => 3
            [post_status] => publish
            [orderby] => rand
        )

    [query_vars] => Array
        (
            [post_type] => post
            [posts_per_page] => 3
            [post_status] => publish
            [orderby] => rand
            [error] => 
            [m] => 
            [p] => 0
            [post_parent] => 
            [subpost] => 
            [subpost_id] => 
            [attachment] => 
            [attachment_id] => 0
            [name] => 
            [pagename] => 
            [page_id] => 0
            [second] => 
            [minute] => 
            [hour] => 
            [day] => 0
            [monthnum] => 0
            [year] => 0
            [w] => 0
            [category_name] => 
            [tag] => 
            [cat] => 
            [tag_id] => 
            [author] => 
            [author_name] => 
            [feed] => 
            [tb] => 
            [paged] => 0
            [meta_key] => 
            [meta_value] => 
            [preview] => 
            [s] => 
            [sentence] => 
            [title] => 
            [fields] => 
            [menu_order] => 
            [embed] => 
            [category__in] => Array
                (
                )

            [category__not_in] => Array
                (
                )

            [category__and] => Array
                (
                )

            [post__in] => Array
                (
                )

            [post__not_in] => Array
                (
                )

            [post_name__in] => Array
                (
                )

            [tag__in] => Array
                (
                )

            [tag__not_in] => Array
                (
                )

            [tag__and] => Array
                (
                )

            [tag_slug__in] => Array
                (
                )

            [tag_slug__and] => Array
                (
                )

            [post_parent__in] => Array
                (
                )

            [post_parent__not_in] => Array
                (
                )

            [author__in] => Array
                (
                )

            [author__not_in] => Array
                (
                )

            [search_columns] => Array
                (
                )

            [ignore_sticky_posts] => 
            [suppress_filters] => 
            [cache_results] => 1
            [update_post_term_cache] => 1
            [update_menu_item_cache] => 
            [lazy_load_term_meta] => 1
            [update_post_meta_cache] => 1
            [nopaging] => 
            [comments_per_page] => 50
            [no_found_rows] => 
            [order] => 
        )

    [tax_query] => WP_Tax_Query Object
        (
            [queries] => Array
                (
                )

            [relation] => AND
            [table_aliases:protected] => Array
                (
                )

            [queried_terms] => Array
                (
                )

            [primary_table] => wp_posts
            [primary_id_column] => ID
        )

    [meta_query] => WP_Meta_Query Object
        (
            [queries] => Array
                (
                )

            [relation] => 
            [meta_table] => 
            [meta_id_column] => 
            [primary_table] => 
            [primary_id_column] => 
            [table_aliases:protected] => Array
                (
                )

            [clauses:protected] => Array
                (
                )

            [has_or_relation:protected] => 
        )

    [date_query] => 
    [request] => 
					SELECT SQL_CALC_FOUND_ROWS  wp_posts.ID
					FROM wp_posts 
					WHERE 1=1  AND wp_posts.post_type = 'post' AND ((wp_posts.post_status = 'publish'))
					
					ORDER BY RAND()
					LIMIT 0, 3
				
    [posts] => Array
        (
            [0] => WP_Post Object
                (
                    [ID] => 4285
                    [post_author] => 4
                    [post_date] => 2023-09-11 12:13:16
                    [post_date_gmt] => 2023-09-11 16:13:16
                    [post_content] => 

Join Stony Brook University’s Intellectual Property Partners on Thursday, October 12, from 4:30 pm to 6 pm at the Charles B. Wang Center at Stony Brook University for the panel discussion titled “Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing.”

The event will be hosted by Intellectual Property Partners (IPP), the SBU Chapter of the National Academy of Inventors (NAI), and the Manufacturing and Technology Resource Consortium (MTRC) and will be followed by a networking cocktail reception from 6 pm to 7 pm.

Moderated by Dr. James Hayward, President, CEO and Chairman of Applied DNA Sciences, panelists include:
– Adrian Howansky, PhD, Clinical Medical Physicist, Department of Radiology, Stony Brook University Hospital
– Doreen Swift, Senior Director, Embedded Software Engineering, IPS
– Michael R. Bielski, President, DevTech Partners
– Nariman Boyle, MD, Director, Ophthalmic Plastic Orbit and Reconstructive Surgery, Department of Ophthalmology, Renaissance School of Medicine, Stony Brook University
– Paul Schwartz, Director, Advanced Propulsion Technologies

This event is free and open to Stony Brook University attendees. Space is limited and registration is required. Register here to secure your spot.

For more information visit: https://www.stonybrook.edu/commcms/ipp/Events/Manufacturing.php

[post_title] => "Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing" 10/12/23 [post_excerpt] => Join Stony Brook University’s Intellectual Property Partners on October 12th for the panel discussion titled “Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing.” [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => bring-your-new-technology-innovations-to-life-through-prototyping-and-manufacturing-10-12-23 [to_ping] => [pinged] => [post_modified] => 2023-11-15 11:24:35 [post_modified_gmt] => 2023-11-15 16:24:35 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=4285 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [1] => WP_Post Object ( [ID] => 3788 [post_author] => 3 [post_date] => 2021-06-03 18:03:30 [post_date_gmt] => 2021-06-03 18:03:30 [post_content] =>

BARDA DRIVe is seeking information on technologies that are relevant to AI for automated biomedical image acquisition and AI for automated biomedical image interpretation, with a focus on reducing the burden on clinical, technician, and care staff in any setting. If you can provide insight on any of the items listed below, please contact Phuong Nguyen (phuong.t.nguyen@stonybrook.edu) by June 8, 2021.

This request encompass all stages of development from early research/academic labs through start up and late commercialization: They are more interested in technical rather than any particular stage of development, thus the focus is not just on the commercial sector but also on the work being conducted at academic/research/medical/FFRDC organizations. This can be an AI solution applied to existing imaging infrastructure, or new imaging devices. This AI and imaging combination should provide new value propositions, form factors, or use cases that are only possible with integration of AI.

Specific areas and use cases of interest include but are not limited to:
- Automated biomedical image interpretation, primarily in ultrasound, computer tomography, and magnetic resonance imaging.
- Approaches to automated interpretation of optical and x-ray images are of interest, but of secondary priority.
- AI-based diagnostic image acquisition and image interpretation in emergency medical services (EMSs) and in surgical settings to accurately assess the severity of a patient’s medical condition, e.g. the location of an internal hemorrhage or the location of a broken bone, torn ligament or other injury.
- AI-based automated image reconstruction.
- AI-based automated analysis of cancer screening images (e.g. mammograms)
- AI-assisted image guidance for placement of medical devices, e.g. catheterization
- AI-assisted fluoroscopy

[post_title] => BARDA RFI/CALL for Technologies [post_excerpt] => BARDA DRIVe is seeking information on technologies that are relevant to AI for automated biomedical image acquisition and AI for automated biomedical image interpretation, with a focus on reducing the burden on clinical, technician, and care staff in any setting. [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => barda-rfi-call-for-technologies [to_ping] => [pinged] => [post_modified] => 2021-09-20 16:11:17 [post_modified_gmt] => 2021-09-20 16:11:17 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=3788 [menu_order] => 43 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 3721 [post_author] => 3 [post_date] => 2021-03-29 13:10:24 [post_date_gmt] => 2021-03-29 13:10:24 [post_content] =>

BARDA DRIVe is seeking information on developments in anticoagulation drugs, assays, and management in the specific context of extracorporeal membrane oxygenation (ECMO) therapy. The intent is to identify areas of innovation that can solve the challenges posed by anticoagulation in ECMO or improve on the ways this issue is currently being addressed. BARDA will not execute any awards based on this notice. This RFI solely aims to gather knowledge on present and future capabilities and other pertinent marketplace data to strengthen BARDA’s understanding of the current developmental landscape of this field. This does not constitute a Request for Proposal (RFP). More information can be found here:
https://beta.sam.gov/opp/e9e7f046d7234dae9f14c1b38a5a20f9/view

The RFI will be open until 04 May 2021, and interested companies should submit their responses to DRIVeContracting@hhs.gov.


[post_title] => BARDA: Call for Information [post_excerpt] => BARDA DRIVe is seeking information on developments in anticoagulation drugs, assays, and management in the specific context of extracorporeal membrane oxygenation (ECMO) therapy. [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => barda-call-for-information [to_ping] => [pinged] => [post_modified] => 2021-09-20 16:11:14 [post_modified_gmt] => 2021-09-20 16:11:14 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=3721 [menu_order] => 51 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 3305 [post_author] => 3 [post_date] => 2019-07-22 13:47:17 [post_date_gmt] => 2019-07-22 13:47:17 [post_content] => Stony Brook University faculty researchers and graduate students involved in research may sign up for a free, 1-day workshop from 8:30-5 on either Aug. 12 or Aug. 15 with the Alan Alda Center for Communicating Science. Workshops are highly interactive and participants must stay the full day. Alda Center workshops empower researchers to communicate their work clearly and vividly to all audiences. The Alda Center has worked with leading researchers from Yale, NASA, and U.S. Fish & Wildlife Service, and many others. SBU reserachers may register via this link: https://forms.gle/fvh3wNLYyQBoeXyi [post_title] => Alda Center Workshop for SBU Researchers [post_excerpt] => Stony Brook University faculty researchers and graduate students involved in research may sign up for a free, 1-day workshop with the Alan Alda Center for Communicating Science. [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => alda-center-workshop-for-sbu-researchers [to_ping] => [pinged] => [post_modified] => 2019-07-22 13:47:17 [post_modified_gmt] => 2019-07-22 13:47:17 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=3305 [menu_order] => 91 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) ) [post_count] => 4 [current_post] => -1 [before_loop] => 1 [in_the_loop] => [post] => WP_Post Object ( [ID] => 4285 [post_author] => 4 [post_date] => 2023-09-11 12:13:16 [post_date_gmt] => 2023-09-11 16:13:16 [post_content] =>

Join Stony Brook University’s Intellectual Property Partners on Thursday, October 12, from 4:30 pm to 6 pm at the Charles B. Wang Center at Stony Brook University for the panel discussion titled “Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing.”

The event will be hosted by Intellectual Property Partners (IPP), the SBU Chapter of the National Academy of Inventors (NAI), and the Manufacturing and Technology Resource Consortium (MTRC) and will be followed by a networking cocktail reception from 6 pm to 7 pm.

Moderated by Dr. James Hayward, President, CEO and Chairman of Applied DNA Sciences, panelists include:
– Adrian Howansky, PhD, Clinical Medical Physicist, Department of Radiology, Stony Brook University Hospital
– Doreen Swift, Senior Director, Embedded Software Engineering, IPS
– Michael R. Bielski, President, DevTech Partners
– Nariman Boyle, MD, Director, Ophthalmic Plastic Orbit and Reconstructive Surgery, Department of Ophthalmology, Renaissance School of Medicine, Stony Brook University
– Paul Schwartz, Director, Advanced Propulsion Technologies

This event is free and open to Stony Brook University attendees. Space is limited and registration is required. Register here to secure your spot.

For more information visit: https://www.stonybrook.edu/commcms/ipp/Events/Manufacturing.php

[post_title] => "Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing" 10/12/23 [post_excerpt] => Join Stony Brook University’s Intellectual Property Partners on October 12th for the panel discussion titled “Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing.” [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => bring-your-new-technology-innovations-to-life-through-prototyping-and-manufacturing-10-12-23 [to_ping] => [pinged] => [post_modified] => 2023-11-15 11:24:35 [post_modified_gmt] => 2023-11-15 16:24:35 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=4285 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [comment_count] => 0 [current_comment] => -1 [found_posts] => 249 [max_num_pages] => 83 [max_num_comment_pages] => 0 [is_single] => [is_preview] => [is_page] => [is_archive] => [is_date] => [is_year] => [is_month] => [is_day] => [is_time] => [is_author] => [is_category] => [is_tag] => [is_tax] => [is_search] => [is_feed] => [is_comment_feed] => [is_trackback] => [is_home] => 1 [is_privacy_policy] => [is_404] => [is_embed] => [is_paged] => [is_admin] => [is_attachment] => [is_singular] => [is_robots] => [is_favicon] => [is_posts_page] => [is_post_type_archive] => [query_vars_hash:WP_Query:private] => 325c4f9f1aebaa5ec90666fa54175ba0 [query_vars_changed:WP_Query:private] => [thumbnails_cached] => [allow_query_attachment_by_filename:protected] => [stopwords:WP_Query:private] => [compat_fields:WP_Query:private] => Array ( [0] => query_vars_hash [1] => query_vars_changed ) [compat_methods:WP_Query:private] => Array ( [0] => init_query_flags [1] => parse_tax_query ) )

“Bring Your New Technology Innovations to Life Through Prototyping and Manufacturing” 10/12/23

More Information

BARDA RFI/CALL for Technologies

More Information

BARDA: Call for Information

More Information

Alda Center Workshop for SBU Researchers

More Information