Long Island Bioscience Hub Reports Significant Impacts

Phase 0 Proof-of-Concept Partnership pilot program demonstrates effectiveness for
transitioning basic science discoveries into the commercialization pipeline.

The Long Island Bioscience Hub (LIBH), a National Institutes of Health (NIH) Research Evaluation and Commercialization Hub (REACH), is pleased to announce it has demonstrated significant impact as outlined in a recent evaluative report presenting the results and activities of the NIH REACH program over the pilot period of three years. The LIBH, a collaboration between Stony Brook University, Brookhaven National Laboratory, Cold Spring Harbor Laboratory, and the Feinstein Institute at Northwell Health, led by the Center for Biotechnology, was formed in March 2015 with a mission to help commercialize biomedical technologies emerging from the region’s research institutions.

The report, prepared independently by RTI International on behalf of the NIH, outlines multiple outcomes from the REACH program, and documents the successes that the LIBH has had during the relatively short pilot phase of its work. The LIBH engaged 600 innovators in training sponsored or co-sponsored by the REACH Program. Fifty technology development projects have been funded by LIBH over the course of three years, including technologies focused on biologic drugs, diagnostic devices, small molecule drugs, therapeutic devices, and Health IT among others. As a result of the NIH investment in the LIBH, ten startup companies have been formed and two license agreements have been executed. In addition, the initial investment made by NIH in the region has generated follow on funding of more than $10 million, $2.8 million coming from five funded SBIR/STTR proposals based on LIBH technologies. This impact from the REACH program contributes to the overall economic impact of Center for Biotechnology, notably $1.2B over a recent fifteen year period.

“We are thrilled with the outcomes reported in the RTI evaluation for the Long Island Bioscience Hub’s efforts thus far under the REACH program” said Clinton T. Rubin, Ph.D., Distinguished Professor, Department of Biomedical Engineering, and Director, Center for Biotechnology. “Through the REACH program we’ve been able to expand on the region’s efforts to commercialize more innovation locally, thereby capturing more of the economic impact within the region. While the pilot program will end in mid-2019, these impacts clearly demonstrate the potential of the model to make significant contributions to our innovation ecosystem.”

“The RTI evaluation reinforces our knowledge that the Long Island Bioscience Hub model has already had a significant, positive impact on technologies and innovators embedded in our research community” stated Dr. Richard Reeder, Vice President for Research at Stony Brook University. “It is imperative we continue to fuel the activities of the LIBH as it is an essential part of innovation economy, and is a significant engine in bringing lifesaving technologies to patients.”

The Center for Biotechnology, in collaboration with other partners in the region, will continue to explore how the model might be continued and expanded.

Click here for PDF version.

SBIR/STTR Omnibus Webinar Recording, Transcript, and Slides Available

The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Program recently hosted a webinar to assist interested applicants with understanding proposal preparation, federal guidelines and resources, the funding process, and address general concerns.

The webinar presentation, recording, and transcript are now available (via web and attachments) for your reference. (Please be advised, an automated transcription service was used, and there may be grammatical errors and typos in the transcript.) We have done our best to correct as many errors as possible, but you are encouraged to reach out to us by email at sbir@od.nih.gov if anything remains unclear.
– Webinar Slides
– Recording
Transcript

HHS SBIR and STTR Omnibus grant solicitations permit researcher-initiated topics around health, medicine and life science to be submitted for funding consideration. With any specific idea, you should speak directly with a HHS SBIR/STTR program manager at least a month BEFORE the deadline to gauge their interest.

You can find the HHS SBIR/STTR Omnibus Solicitations, and all of other SBIR/STTR solicitations on the Funding page of the SBIR/STTR Website: https://sbir.nih.gov/funding.

Be sure to also check the targeted funding announcements page, https://sbir.nih.gov/funding/individual-announcements. NIH Institutes and Centers will issue targeted SBIR/STTR grant solicitations around specific, high-priority research areas.

The next submission deadline is September 5, 2019.

DRIVe Special Instructions & EZ-BAA Updates

Two important updates regarding upcoming BARDA DRIVe funding opportunities: 

Drive Special Instructions – Due May 28!
White papers, quad chart, and application form for the DRIVe special instructions to the BARDA BAA are due by 3:00 PM ET on Tuesday May 28th, 2019.
Focus areas are:
• 15.1: Advanced Research and Development of Sepsis Diagnostics and Devices
• 15.2: Post-sepsis Monitoring
• 16.1: On-Person, Wearable, and Biosensing Devices (Host Response and Direct Pathogen Detection)

Steps to apply:
1.Review Solicitation BAA-18-100-SOL-00003 on fbo.gov.
2.Schedule a meeting with the ENACT or Solving Sepsis team (strongly encouraged).
3.Download the DRIVe Special Instructions Submission Form.*
4.Complete the PDF form, Quad Chart, White Paper, and Addendum (ROM cost estimate).
5. Email your submission to DRIVeContracting@hhs.gov by 3:00PM ET on May 28th.
6. You will receive an email notification confirming receipt within 5 business days. DRIVe personnel will review your white paper as described in the solicitation.
7. DRIVe personnel will notify you of the outcome of that review and may invite you to submit a full proposal.
*You must download the PDF, as filling it out in a browser window will disable some key functionality.

General DRIVe EZ-BAA – Deadline Extended 
The deadline for DRIVe’s EZ-BAA has been extended to 3:00 PM ET on November 15th, 2019. Applications are reviewed on a rolling basis with a response as early as 30 days after submission.

DRIVe has a new online portal for submitting EZ-BAA. Note: Companies must register for a profile in the online portal here, it can take up to 1 business day to account to be created.

Innovation Manufacturing Grants

The next round of Jeff Lawrence Innovation Fund Manufacturing Grants will open on May 1, 2019!  Manufacturing Grants are designed to encourage collaboration between companies and non-profit organizations in New York State that work with the manufacturing industry.

Eligible applicants include New York State not-for-profit organizations and applicants must partner with a New York State small or medium sized (SME) manufacturer or other early-stage company with a project relevant to the manufacturing sector. For the purposes of this grant, SME is defined as a business with at least one physical establishment in New York State, and no more than 500 employees across the entire firm or enterprise worldwide.

Eligible projects will include those that are used by the applicant to assist companies with the following types of projects: adoption of new technology to enhance a process and/or product, Prototype development, Design for manufacturing, Proof-of-concept manufacturing, Manufacturing scale-up
Manufacturing-related equipment purchases [4] [5], and other projects to advance manufacturing or manufacturing capabilities

Awards will be selected in July. Visit https://fuzehub.com/manufacturing-grants/ for full details.

 

Call for Entrepreneurs!

Thinking of starting a life science company? The Center for Biotechnology can provide access to a compelling, pre-screened pipeline of academic technologies, milestone based incentives, access to early-stage funding opportunities, and staff support to serve as your virtual start-up team.

The Long Island, NY region has a well demonstrated capacity for innovation, serving as home to Cold Spring Harbor Laboratory, Stony Brook University, the Feinstein Institute at Northwell Health, and Brookhaven National Laboratory, among others. Sample technologies that have emerged from the region include Magnetic Resonance Imaging (MRI), ReoPro®; Xiaflex®; Cavistat®; Oracea®, and 3D Virtual Colonoscopy.

More details on the BioEntrepreneur-in-Residence initiative can be found here. Women and underrepresented minorities are encouraged to inquire. If you are interested in the initiative or would like to discuss further, please contact Diane Fabel at diane.fabel@stonybrook.edu or call 631.632.1582.