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CFB Announces Annual Applied Research & Development (ARaD) Awards

The Center for Biotechnology at Stony Brook University (CFB) has announced the recipients of the 2023-2024 Applied Research & Development (ARaD) awards. The ARaD Program is designed to help bridge the gap between the early-stage technology discovery and development capabilities of the academic community, and the later-stage commercial development interests of the bioscience industry.

The CFB is supporting the project*, “Wearable Haptic Device for Catheter Based Cardiac Procedures” that is being developed by HapticHeart Solutions. The company is collaborating with Dr. Wei Lin of the Department of Biomedical Engineering to upgrade the haptic handle of their current prototype to a sleek wearable device for a better experience and reduced cost. The technology has the potential to revolutionize the $14B cardiac catheterization market.

Additionally, the CFB will support the project* entitled “”Development of a Structural Model and Enzyme-Inhibitor Interactions for a Novel Cancer Target” by Lime Therapeutics, a startup spun out of Memorial Sloan Kettering Cancer Center, in collaboration with Dr. Ivet Bahar, who serves as the Louis and Beatrice Laufer Chair and Director Laufer Center for Physical & Quantitative Biology within the Department of Biochemistry and Cell Biology at Stony Brook University. The goal of this project is to leverage the computational and molecular dynamics capabilities of Dr. Bahar’s lab to achieve three specific aims related to optimizing the company’s lead compound.

The program currently provides matching funds on a competitive basis to support collaborations between Stony Brook University faculty and New York State corporate partners in all areas of medical biotechnology. The primary interest is in supporting development of technologies that will help companies hit commercially relevant milestones, and that have the potential to positively impact the New York State economy.

Companies that are looking to connect with expertise at Stony Brook University are encouraged to contact Dr. Phuong Nguyen at the Center for Biotechnology to explore options. Dr. Nguyen can be reached at: phuong.t.nguyen@stonybrook.edu.

*pending finalization of contract

View the full press release here.

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Governor Kathy Hochul has unveiled plans for New York BioGenesis Park, a groundbreaking $430 million Cell and Gene Therapy (CGT) Innovation Hub in Nassau County, Long Island. To be developed by The Albanese Organization, Inc., this state-of-the-art facility would catalyze CGT research, development, clinical manufacturing, and commercialization across New York State. With a historic $150 million state investment—the largest nationwide for a cell and gene therapy hub—NYBGP would accelerate the delivery of new therapies from lab to patient in New York's diverse communities. This transformative hub aims to establish New York as the leading global destination for CGT innovation, driving economic growth, attracting top talent, and revolutionizing patient care statewide and beyond.

The Center for Biotechnology is thrilled to be counted as a partner in this effort, and is looking forward to working with our colleagues in the initiative to help catalyze and accelerate life-changing therapies.

New York BioGenesis Park is envisioned as a cutting-edge, full-service campus dedicated to advancing cell and gene therapies and accelerating their commercialization. At full build-out, the 700,000-square-foot park would create an end-to-end Cell and Gene Therapy innovation and supply center, featuring interconnected areas for public engagement, research, manufacturing, and collaboration.

A cornerstone of New York BioGenesis Park is its incubator, supported by a $50 million investment from ESD's Long Island Investment Fund. This facility will empower early-stage therapeutic developers by offering state-of-the-art wet lab space, shared equipment, office space, and other essential resources. This nurturing environment will provide Cell and Gene Therapy companies with access to specialized equipment, mentoring, and stage-appropriate financial guidance. As a critical component of New York BioGenesis Park, the incubator is poised to catalyze the growth of promising Cell and Gene Therapy companies by providing them with resources and support, unlocking their potential for innovation and success.

New York BioGenesis Park would foster strong ties with academic and medical institutions throughout New York, creating a robust ecosystem for Cell and Gene Therapy innovation. Collaborating with the Empire State Cellular Therapy Consortium and world-class institutions like Cold Spring Harbor Laboratory, the Feinstein Institutes, Northwell Health, Roswell Park, Stony Brook University, Weill Cornell, Columbia University and others around the state, New York BioGenesis Park would enhance research synergies and accelerate medical breakthroughs. This ecosystem would bring together experts in advanced Cell and Gene Therapy therapies, offering specialized facilities, services, and resources to both tenants and collaborating institutions. By facilitating cutting-edge science, innovative technology development and novel approaches to clinical trials, New York BioGenesis Park would ensure New York's institutions remain globally competitive in groundbreaking Cell and Gene Therapy research and commercialization.

Read the press release of Governor Hochul's announcement here:
https://www.governor.ny.gov/news/governor-hochul-launches-next-phase-long-islands-nation-leading-cell-and-gene-therapy

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Kathera Bioscience Inc., a privately-held biotech startup was awarded a SBIR Fast Track grant with a value of up to $3,298,530 from the National Institute of Allergy and Infectious Diseases (NIAID) for its dihydrofolate reductase (DHFR) program. Kathera Bioscience was founded by CFB Advisor and Long Island BIoMentor Initiative Mentor Dr. Stephen Parent.

Kathera is developing novel therapeutics to treat fungal infections, a major cause of human disease with an estimated 11.5 million annual life-threatening infections globally, resulting in more than 1.5 million deaths. The award will fund selection of a lead series in the Phase 1 award and lead optimization in Phase 2. Read more about Kathera and the award here.

[post_title] => Kathera Bioscience Receives SBIR Phase I Fast Track Award To Advance Novel Drugs To Treat Life Threatening Fungal Infections [post_excerpt] => Kathera Bioscience Inc.,founded by CFB Advisor and Long Island BIoMentor Initiative Mentor Dr. Stephen Parent, was awarded a SBIR Fast Track grant with a value of up to $3,298,530. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => kathera-phase2-2024 [to_ping] => [pinged] => [post_modified] => 2024-12-10 13:52:57 [post_modified_gmt] => 2024-12-10 18:52:57 [post_content_filtered] => [post_parent] => 0 [guid] => https://centerforbiotechnology.org/?p=4380 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 2344 [post_author] => 3 [post_date] => 2016-07-14 13:50:02 [post_date_gmt] => 2016-07-14 13:50:02 [post_content] => Traverse Biosciences has announced a collaboration with SUNY Updated Medical University on a $164,689 Peer Reviewed Medical Research Program (PRMRP) Discovery Award from the U.S. Department of Defense. The research will be led by Gary Nieman, Associate Professor and Senior Research Scientist in the Department of Surgery and will evaluate the effectiveness of the company’s lead drug candidate, TRB-N0224, to treat acute lung injury, including acute respiratory distress syndrome (ARDS). Read more here. TraverseBioLogo2 [post_title] => Traverse Biosciences to collaborate with SUNY Upstate Medical University [post_excerpt] => Traverse Biosciences has announced a collaboration with SUNY Updated Medical University on a Peer Reviewed Medical Research Program (PRMRP) Discovery Award from the U.S. Department of Defense. [post_status] => publish [comment_status] => open [ping_status] => open [post_password] => [post_name] => traverse-biosciences-to-collaborate-with-suny-upstate-medical-university [to_ping] => [pinged] => [post_modified] => 2016-07-14 13:50:27 [post_modified_gmt] => 2016-07-14 13:50:27 [post_content_filtered] => [post_parent] => 0 [guid] => http://centerforbiotechnology.org/?p=2344 [menu_order] => 171 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 4477 [post_author] => 4 [post_date] => 2024-09-10 13:59:15 [post_date_gmt] => 2024-09-10 17:59:15 [post_content] =>

Established in April 2023, Stony Brook University's Center for Healthy Aging aims to promote healthy aging and extend physical and mental well-being through innovative research solutions. Please join them for our inaugural virtual seminar series.

Dr. Payel Sen, Stadtman Investigator, NIH
Epigenetic mechanisms of tissue aging
September 25th at 11 am
https://stonybrook.zoom.us/j/98037022918?pwd=XT2p35EKbehaazZpb0aLJtOW3a8gE1.1
Meeting ID: 980 3702 2918
Passcode: 426599

As we age, changes in our “epigenome” alter how our genes are regulated, ultimately impacting organ function. Our research focuses on understanding epigenomic changes in different organs. In this presentation, I will focus on skeletal muscle, which makes up 40% of our body weight and plays a key role in metabolism. As we age, our muscles tend to weaken, partly because the stem cells in our muscles that help repair and grow reduce in number and function. In our study, we looked at muscle stem cells from young, old, and geriatric mice and uncovered that as these cells age, they show signs of increased immune activity and start to lose their ability to stay dormant, which is vital for their function. We also identified specific areas of the genome that might be responsible for these changes. By targeting these areas, we could potentially restore the function of these stem cells and help maintain muscle health as we age.

Upcoming Topics & Dates:

  • October 30th, 11 am: Samantha Rossano, PhD, Medical Science Liaison, Life Molecular Imaging, Inc., Brain imaging biomarkers in Alzheimer’s disease
  • November 20th, 11 am: Gregorio Valdez, PhD, GLF Translational Associate Professor of Molecular Biology, Cell Biology and Biochemistry, Brown University, Slowing muscle degeneration
  • February 26th, 11 am: Christopher Barrett Bowling, MD, MSPH, Associate Professor of Medicine, Associate Professor in Population Health Sciences, Senior Fellow of the Center for the Study of Aging and Human Development, Duke University, Geriatricizing chronic disease research
  • March 26th, 11 am: Dr. Frank Lin, MD, PhD, Director of the Cochlear Center for Hearing and Public Health, Professor of Otolaryngology, Medicine, Mental Health, and Epidemiology, Johns Hopkins University Team, Baltimore HEARS and the Baltimore Longitudinal Study of Aging
  • April 30th, 11 am: Dennis Selkoe, MD, Vincent and Stella Coates Professor of Neurologic Diseases, Harvard University, Role of soluble oligomers of amyloid beta in synaptic injury

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Governor Kathy Hochul has unveiled plans for New York BioGenesis Park, a groundbreaking $430 million Cell and Gene Therapy (CGT) Innovation Hub in Nassau County, Long Island. To be developed by The Albanese Organization, Inc., this state-of-the-art facility would catalyze CGT research, development, clinical manufacturing, and commercialization across New York State. With a historic $150 million state investment—the largest nationwide for a cell and gene therapy hub—NYBGP would accelerate the delivery of new therapies from lab to patient in New York's diverse communities. This transformative hub aims to establish New York as the leading global destination for CGT innovation, driving economic growth, attracting top talent, and revolutionizing patient care statewide and beyond.

The Center for Biotechnology is thrilled to be counted as a partner in this effort, and is looking forward to working with our colleagues in the initiative to help catalyze and accelerate life-changing therapies.

New York BioGenesis Park is envisioned as a cutting-edge, full-service campus dedicated to advancing cell and gene therapies and accelerating their commercialization. At full build-out, the 700,000-square-foot park would create an end-to-end Cell and Gene Therapy innovation and supply center, featuring interconnected areas for public engagement, research, manufacturing, and collaboration.

A cornerstone of New York BioGenesis Park is its incubator, supported by a $50 million investment from ESD's Long Island Investment Fund. This facility will empower early-stage therapeutic developers by offering state-of-the-art wet lab space, shared equipment, office space, and other essential resources. This nurturing environment will provide Cell and Gene Therapy companies with access to specialized equipment, mentoring, and stage-appropriate financial guidance. As a critical component of New York BioGenesis Park, the incubator is poised to catalyze the growth of promising Cell and Gene Therapy companies by providing them with resources and support, unlocking their potential for innovation and success.

New York BioGenesis Park would foster strong ties with academic and medical institutions throughout New York, creating a robust ecosystem for Cell and Gene Therapy innovation. Collaborating with the Empire State Cellular Therapy Consortium and world-class institutions like Cold Spring Harbor Laboratory, the Feinstein Institutes, Northwell Health, Roswell Park, Stony Brook University, Weill Cornell, Columbia University and others around the state, New York BioGenesis Park would enhance research synergies and accelerate medical breakthroughs. This ecosystem would bring together experts in advanced Cell and Gene Therapy therapies, offering specialized facilities, services, and resources to both tenants and collaborating institutions. By facilitating cutting-edge science, innovative technology development and novel approaches to clinical trials, New York BioGenesis Park would ensure New York's institutions remain globally competitive in groundbreaking Cell and Gene Therapy research and commercialization.

Read the press release of Governor Hochul's announcement here:
https://www.governor.ny.gov/news/governor-hochul-launches-next-phase-long-islands-nation-leading-cell-and-gene-therapy

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Long Island to be location for Nation-Leading Cell and Gene Therapy Innovation Hub: New York BioGenesis Park.

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